NICOTINE†
| Chemical Identification | |
|---|---|
| CAS # | 54-11-5 |
| Formula |
C₁₀H₁₄N₂ |
| Synonyms |
3-(1-methyl-2-pyrrolidyl)pyridine |
| Physical Properties | |||
|---|---|---|---|
| Physical description | Pale-yellow to dark-brown liquid with a fish-like odor when warm. | ||
| Boiling point | 476.1°F at 745 mmHg | Molecular weight | 162.2 |
| Freezing point/melting point | -110°F | Vapor pressure | 0.08 mmHg |
| Flash point | 203°F | Vapor density | 5.61 |
| Specific gravity | 1.01 | Ionization potential | 8.01 eV |
| Lower explosive limit (LEL) | 0.7% | Upper explosive limit (UEL) | 4.0% |
| NFPA health rating | 3 | NFPA fire rating | 1 |
| NFPA reactivity rating | 0 | NFPA special instruction | |
| Vapor hazard ratio (VHR) | |||
| Historical exceedance percentage | |||
| Target organs | |||
| Monitoring Methods Used by OSHA | ||||||
|---|---|---|---|---|---|---|
| Analyte code (IMIS no.) | 1855 | |||||
| Sampling group | ||||||
| Sampler/Sampling media | XAD-4 tube (80/40 mg) [SKC 226-93] | |||||
| Sampling time* |
480 min |
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| Sampling volume (TWA)* |
0.5-600 L |
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| Sampling flow rate (TWA)* |
0.1-1 L/min |
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| Sampling volume (STEL/Peak/C)* |
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| Sampling flow rate (STEL/Peak/C)* |
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| Analytical method instruments | GC-NPD | |||||
| Method reference | NIOSH 2551 (partially validated) | |||||
| Notes |
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| Special requirements |
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* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.
| Wipe Method | |
|---|---|
| Sampler/Sampling media |
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| Bulk Method |
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| On-Site Screening Techniques | ||||||
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| Device | ||||||
| Model/Type | ||||||
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Sampling information (see manufacturer instructions) |
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| Exposure Limits | |||||||
|---|---|---|---|---|---|---|---|
|
OSHA PEL
8-hour TWA (ST) STEL (C) Ceiling Peak |
NIOSH REL
Up to 10-hour TWA (ST) STEL (C) Ceiling |
ACGIH TLV©
8-hour TWA (ST) STEL (C) Ceiling |
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| PEL-TWA |
0.5 mg/m³ |
REL-TWA |
0.5 mg/m³ |
TLV-TWA |
0.05 mg/m³ [1992] |
PEL-TWA |
0.075 ppm (0.5 mg/m³) |
| PEL-STEL |
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REL-STEL |
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TLV-STEL |
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PEL-STEL |
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| PEL-C |
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REL-C |
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TLV-C |
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PEL-C |
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| Skin notation |
Y |
Skin notation |
Y |
Skin notation |
Y |
Skin notation |
Y |
| Notes: |
Notes:
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Notes:
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Notes:
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| Health factors: See NIH-NLM PubChem. | IDLH |
5 mg/m³ |
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| Carcinogenic classifications: Not listed |
Notes:
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AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
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| Additional Resources and Literature References |
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NOAA: CAMEO Chemicals - (-)-Nicotine NIOSH: Pocket Guide to Chemical Hazards - Nicotine Literature References
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Last Updated Date : 01/05/2021