NICOTINE†
| CAS # | 54-11-5 |
|---|---|
| Formula |
C₁₀H₁₄N₂ |
| Synonyms |
3-(1-methyl-2-pyrrolidyl)pyridine |
| Physical description | Pale-yellow to dark-brown liquid with a fish-like odor when warm. | ||
|---|---|---|---|
| Boiling point | 476.1°F at 745 mmHg | Molecular weight | 162.2 |
| Freezing point/melting point | -110°F | Vapor pressure | 0.08 mmHg |
| Flash point | 203°F | Vapor density | 5.61 |
| Specific gravity | 1.01 | Ionization potential | 8.01 eV |
| Lower explosive limit (LEL) | 0.7% | Upper explosive limit (UEL) | 4.0% |
| NFPA health rating | 3 | NFPA fire rating | 1 |
| NFPA reactivity rating | 0 | NFPA special instruction | |
| Vapor hazard ratio (VHR) | |||
| Historical exceedance percentage | |||
| Target organs | |||
| Analyte code (IMIS no.) | 1855 |
|---|---|
| Sampling group | |
| Sampler/Sampling media | XAD-4 tube (80/40 mg) [SKC 226-93] |
| Sampling time* |
480 min |
| Sampling volume (TWA)* |
0.5-600 L |
| Sampling flow rate (TWA)* |
0.1-1 L/min |
| Sampling volume (STEL/Peak/C)* |
|
| Sampling flow rate (STEL/Peak/C)* |
|
| Analytical method instruments | GC-NPD |
| Method reference | NIOSH 2551 (partially validated) |
| Notes |
|
| Special requirements |
|
* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.
| Wipe Sampler/Sampling media |
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|---|---|
| Bulk Method |
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| Device | |||||
|---|---|---|---|---|---|
| Model/Type | |||||
|
Sampling information (see manufacturer instructions) |
|
OSHA PEL
8-hour TWA (ST) STEL (C) Ceiling Peak |
NIOSH REL
Up to 10-hour TWA (ST) STEL (C) Ceiling |
ACGIH TLV©
8-hour TWA (ST) STEL (C) Ceiling |
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|---|---|---|---|---|---|---|---|
| PEL-TWA |
0.5 mg/m³ |
REL-TWA |
0.5 mg/m³ |
TLV-TWA |
0.05 mg/m³ [1992] |
PEL-TWA |
0.075 ppm (0.5 mg/m³) |
| PEL-STEL |
|
REL-STEL |
|
TLV-STEL |
|
PEL-STEL |
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| PEL-C |
|
REL-C |
|
TLV-C |
|
PEL-C |
|
| Skin notation |
Y |
Skin notation |
Y |
Skin notation |
Y |
Skin notation |
Y |
| Notes: |
Notes:
|
Notes:
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Notes:
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| Health factors: See NIH-NLM PubChem. | IDLH |
5 mg/m³ |
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| Carcinogenic classifications: Not listed |
Notes:
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|
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
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Additional Resources and Literature References
|
NOAA: CAMEO Chemicals - (-)-Nicotine NIOSH: Pocket Guide to Chemical Hazards - Nicotine Literature References
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Last Updated Date : 01/05/2021