NICOTINE†

Chemical Identification
Chemical Identification
CAS # 54-11-5
Formula

C₁₀H₁₄N₂

Synonyms
 

3-(1-methyl-2-pyrrolidyl)pyridine

Physical Properties
Physical Properties
Physical description Pale-yellow to dark-brown liquid with a fish-like odor when warm.
Boiling point 476.1°F at 745 mmHg Molecular weight 162.2
Freezing point/melting point -110°F Vapor pressure 0.08 mmHg
Flash point 203°F Vapor density 5.61
Specific gravity 1.01 Ionization potential 8.01 eV
Lower explosive limit (LEL) 0.7% Upper explosive limit (UEL) 4.0%
NFPA health rating 3 NFPA fire rating 1
NFPA reactivity rating 0 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 1855
Sampling group
Sampler/Sampling media XAD-4 tube (80/40 mg) [SKC 226-93]
Sampling time*
 

480 min

Sampling volume (TWA)*
 

0.5-600 L

Sampling flow rate (TWA)*
 

0.1-1 L/min

Sampling volume (STEL/Peak/C)*
 

 

Sampling flow rate (STEL/Peak/C)*
 

 

Analytical method instruments GC-NPD
Method reference NIOSH 2551 (partially validated)
Notes
 

 

Special requirements
 

 

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
 

 

Bulk Method
Bulk Method
 

 

On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA
 

0.5 mg/m³

REL-TWA
 

0.5 mg/m³

TLV-TWA
 

0.05 mg/m³ [1992]

PEL-TWA
 

0.075 ppm (0.5 mg/m³)

PEL-STEL
 

 

REL-STEL
 

 

TLV-STEL
 

 

PEL-STEL
 

 

PEL-C
 

 

REL-C
 

 

TLV-C
 

 

PEL-C
 

 

Skin notation
 

Y

Skin notation
 

Y

Skin notation
 

Y

Skin notation
 

Y

Notes:
 

See 29 CFR 1910.1000 Table Z-1.

Notes:
 

 

Notes:
 

 

Notes:
 

 

Health factors:  See NIH-NLM PubChem. IDLH
 

5 mg/m³

Carcinogenic classifications: Not listed Notes:
 

 

AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
 

 

Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - (-)-Nicotine

NIOSH: Pocket Guide to Chemical Hazards - Nicotine

Literature References

 
  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Nicotine. See annual publication for most recent information.

Last Updated Date : 01/05/2021