1. OSHA Occupational Chemical Database
  2. ETHYL BUTYL KETONE (3-HEPTANONE)
Label abbreviations descriptions

ETHYL BUTYL KETONE (3-HEPTANONE)†

Chemical Identification
Chemical Identification
CAS # 106-35-4
Formula

CH₃CH₂CO[CH₂]₃CH₃
Synonyms

butyl ethyl ketone; 3-heptanone
Physical Properties
Physical Properties
Physical description Colorless liquid with a fruity odor.
Boiling point 298°F Molecular weight 114.2
Freezing point/melting point -38°F Vapor pressure 4 mmHg
Flash point 115°F (open cup) Vapor density
Specific gravity 0.82 Ionization potential 9.02 eV
Lower explosive limit (LEL) Upper explosive limit (UEL)
NFPA health rating 2 NFPA fire rating 2
NFPA reactivity rating 0 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 1100
Sampling group
Sampler/Sampling media CSC tube (100/50 mg) [SKC 226-01]
Sampling time*
Sampling volume (TWA)*

1-25 L
Sampling flow rate (TWA)*

0.01-0.2 L/min
Sampling volume (STEL/Peak/C)*
 

 
Sampling flow rate (STEL/Peak/C)*
Analytical method instruments GC-FID
Method reference NIOSH 1301 (partially validated)
Notes
 

 
Special requirements
 

 

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
 

 
Bulk Method
Bulk Method
 

 
On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA
 

50 ppm (230 mg/m³)

 REL-TWA
 

50 ppm (230 mg/m³)

 TLV-TWA
 

50 ppm [1995]

 PEL-TWA
 

50 ppm (230 mg/m³)
PEL-STEL
 

 

 REL-STEL
 

 

 TLV-STEL
 

75 ppm [1995]

 PEL-STEL
 

75 ppm (345 mg/m³)
PEL-C
 

 

 REL-C
 

 

 TLV-C
 

 

 PEL-C
 

 
Skin notation
 

N

 Skin notation
 

N

 Skin notation
 

N

 Skin notation
 

N
Notes:
 

See 29 CFR 1910.1000 Table Z-1.

 Notes:
 

 

 Notes:
 

 

 Notes:
 

 
Health factors:  See NIH-NLM PubChem. IDLH
 

1000 ppm
Carcinogenic classifications: Not listed Notes:
 

 
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
 

 
Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Ethyl butyl ketone

NIOSH: Pocket Guide to Chemical Hazards - Ethyl butyl ketone

Literature References

 
  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Ethyl Butyl Ketone. See annual publication for most recent information.
  • California Occupational Safety & Health Standards Board: Initial [64 KB PDF, 12 pages] and Final [76 KB PDF, 13 pages] Statement of Reasons. November 3, 2004.
  • Pohanish, R.P. (editor): Ethyl Butyl Ketone. In Sittig’s Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, pp. 1062-1064, 2002.
  • NIOSH: Occupational Health Guideline for Ethyl Butyl Ketone. September 1978.

Last Updated Date : 12/28/2020