Lapse in Appropriations
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ISOPHORONE DIISOCYANATE
| CAS # | 4098-71-9 |
|---|---|
| Formula |
C₁₂H₁₈N₂O₂ |
| Synonyms |
IPDI, isocyanic acid, methylene (3,5,5-trimethyl-3,1-cyclohexylene) ester, 3-isocyanatomethyl-3,5,5-trimethylcyclohexyl-isocyanate, isophorone diamine diisocyanate |
| Physical description | Colorless to slightly yellow liquid with a pungent odor. | ||
|---|---|---|---|
| Boiling point | Molecular weight | 222.3 | |
| Freezing point/melting point | -76°F | Vapor pressure | 0.0003 mmHg |
| Flash point | 311°F | Vapor density | |
| Specific gravity | 1.06 | Ionization potential | |
| Lower explosive limit (LEL) | Upper explosive limit (UEL) | ||
| NFPA health rating | 2 | NFPA fire rating | 1 |
| NFPA reactivity rating | 1 | NFPA special instruction | W: Reacts violently or explosively with water. |
| Vapor hazard ratio (VHR) | |||
| Historical exceedance percentage | |||
| Target organs | |||
| Analyte code (IMIS no.) | 1539 |
|---|---|
| Sampling group | |
| Sampler/Sampling media | Isocyanate Sampling Filter Kit - GFF (37 mm, open-faced) coated with 1 mg 1-(2-pyridyl)piperazine [SLTC103] |
| Sampling time* | 15 min |
| Sampling volume (TWA)* | 15 L |
| Sampling flow rate (TWA)* | 1 L/min |
| Sampling volume (STEL/Peak/C)* | |
| Sampling flow rate (STEL/Peak/C)* | |
| Analytical method instruments | UHPLC |
| Method reference | OSHA 5002 (fully validated) |
| Notes | Refrigerate coated filters until used. Sample open-faced!! |
| Special requirements |
* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.
| Wipe Sampler/Sampling media | |
|---|---|
| Bulk Method |
| Device | Hazard Assessment Test Kit for Aliphatic Isocyanates |
|---|---|
| Model/Type | 769-1003 |
|
Sampling information (see manufacturer instructions) |
Isocyanate Surface and Dermal Sampling, Hazard Assessment Test Kit for Aliphatic Isocyanates |
|
OSHA PEL
8-hour TWA (ST) STEL (C) Ceiling Peak |
NIOSH REL
Up to 10-hour TWA (ST) STEL (C) Ceiling |
ACGIH TLV©
8-hour TWA (ST) STEL (C) Ceiling |
|||||
|---|---|---|---|---|---|---|---|
| PEL-TWA | REL-TWA |
0.005 ppm (0.045 mg/m³) |
TLV-TWA |
0.005 ppm [1985] |
PEL-TWA |
0.005 ppm (0.045 mg/m³) |
|
| PEL-STEL | REL-STEL |
0.02 ppm (0.180 mg/m³) |
TLV-STEL | PEL-STEL |
0.02 ppm |
||
| PEL-C | REL-C | TLV-C | PEL-C | ||||
| Skin notation |
N |
Skin notation |
Y |
Skin notation |
N |
Skin notation |
Y |
|
Notes:
Not established |
Notes: | Notes: | Notes: | ||||
| Health factors: See NIH-NLM PubChem. | IDLH | ||||||
| Carcinogenic classifications: Not listed | Notes: | ||||||
| AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3: | |||||||
Additional Resources and Literature References
|
NOAA: CAMEO Chemicals - Isophorone diisocyanate NIOSH: Pocket Guide to Chemical Hazards - Isophorone diisocyanate Literature References
|
Last Updated Date : 04/02/2025