DIAZOMETHANE†

Chemical Identification
Chemical Identification
CAS # 334-88-3
Formula

CH₂N₂

Synonyms

azimethylene; azomethylene; diazirine

Physical Properties
Physical Properties
Physical description Yellow gas with a musty odor.
Boiling point -9°F Molecular weight 42.1
Freezing point/melting point -229°F Vapor pressure >1 atm
Flash point Vapor density 1.45
Specific gravity Ionization potential 9.00 eV
Lower explosive limit (LEL) Upper explosive limit (UEL)
NFPA health rating NFPA fire rating
NFPA reactivity rating NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 0861
Sampling group
Sampler/Sampling media XAD-2 tube (100/50 mg) coated with octanoic acid [SKC 226-23]
Sampling time*
Sampling volume (TWA)*

6-30 L

Sampling flow rate (TWA)*

0.2 L/min

Sampling volume (STEL/Peak/C)*
Sampling flow rate (STEL/Peak/C)*
Analytical method instruments GC-FID
Method reference NIOSH 2515 (partially validated)
Notes
Special requirements

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
Bulk Method
Bulk Method
On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA

0.2 ppm (0.4 mg/m³)

REL-TWA

0.2 ppm (0.4 mg/m³)

TLV-TWA

0.2 ppm [1970]

PEL-TWA

0.2 ppm (0.4 mg/m³)

PEL-STEL REL-STEL TLV-STEL PEL-STEL
PEL-C REL-C TLV-C PEL-C
Skin notation

N

Skin notation

N

Skin notation

N

Skin notation

N

Notes:

See 29 CFR 1910.1000 Table Z-1.

Notes: Notes: Notes:
Health factors:  See NIH-NLM PubChem. IDLH

2 ppm

Carcinogenic classifications: IARC-3, TLV-A2 Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Diazomethane

NIOSH: Pocket Guide to Chemical Hazards - Diazomethane

Literature References

  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Diazomethane. See annual publication for most recent information.
  • Occupational Health Guidelines for Chemical Hazards. US Department of Health and Human Services (DHHS), National Institute for Occupational Safety and Health (NIOSH) Publication No. 81-123, (1981, January). Provides a table of contents of guidelines for many hazardous chemicals. The files provide technical chemical information, including chemical and physical properties, health effects, exposure limits, and recommendations for medical monitoring, personal protective equipment (PPE), and control procedures.

Last Updated Date : 12/22/2020