2-CHLORO-6-(TRICHLOROMETHYL) PYRIDINE (NITRAPYRIN)†

Chemical Identification
Chemical Identification
CAS # 1929-82-4
Formula

C₆H₃Cl₄N

Synonyms

2-chloro-6-(trichloro-methyl)pyridine; N-serve; 2,2,2,6-tetrachloro-2-picoline

Physical Properties
Physical Properties
Physical description Colorless or white, crystalline solid with a mild, sweet odor.
Boiling point 277 to 280°F at 11 mmHg Molecular weight 230.9
Freezing point/melting point 145°F Vapor pressure 0.003 mmHg at 73°F
Flash point Vapor density
Specific gravity Ionization potential
Lower explosive limit (LEL) Upper explosive limit (UEL)
NFPA health rating NFPA fire rating
NFPA reactivity rating NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 9135 (total dust) 9130 (respirable dust)
Sampling group
Sampler/Sampling media Tared low-ash 37 mm PVC filter, 5 microns [SLTC108] Tared low-ash 37 mm PVC filter, 5 microns, preceded by 10 mm nylon Dorr-Oliver cyclone for respirable samples. [SLTC108]
Sampling time*

240-480 min

 

240-480 min

Sampling volume (TWA)*

960 L

 

816 L

Sampling flow rate (TWA)*

2 L/min

 

1.7 L/min ±5%

Sampling volume (STEL/Peak/C)*
 

 

Sampling flow rate (STEL/Peak/C)*
 

 

Analytical method instruments Gravimetric Gravimetric
Method reference OSHA PV2121 (partially validated) OSHA PV2121 (partially validated)
Notes

If the net weight of the sample yields a concentration below the PEL after considering the associated SAE , the SLTC will perform no further work on the sample and the sample air concentration will be reported as the calculated gravimetric air concentration.

If the net weight corresponds to an amount greater than the PEL value after considering the associated SAE, the sample may be analyzed for  the applicable component and appropriate results will be reported.

 

 

If the filter is not overloaded, samples can be collected up to an 8-hour period. If the net weight of the sample yields a concentration below the PEL after considering the associated SAE , the SLTC will perform no further work on the sample and the sample air concentration will be reported as the calculated gravimetric air concentration.

If the net weight corresponds to an amount greater than the PEL value after considering the associated SAE, the sample may be analyzed for  the applicable component and appropriate results will be reported.

Special requirements
 

FOR TOTAL DUST, DO NOT USE A CYCLONE!!

 

 

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
 

 

Bulk Method
Bulk Method
 

 

On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA
 

5 mg/m³ (respirable fraction), 15 mg/m³ (total dust)

REL-TWA
 

10 mg/m³ (total dust), 5 mg/m³ (respirable fraction)

TLV-TWA
 

10 mg/m³ (inhalable fraction and vapor) [1992]

PEL-TWA
 

10 mg/m³ (total dust), 5 mg/m³ (respirable fraction)

PEL-STEL
 

 

REL-STEL
 

20 mg/m³

TLV-STEL
 

20 mg/m³ (inhalable fraction and vapor) [1992]

PEL-STEL
 

 

PEL-C
 

 

REL-C
 

 

TLV-C
 

 

PEL-C
 

 

Skin notation
 

N

Skin notation
 

N

Skin notation
 

N

Skin notation
 

N

Notes:
 

See CFR 1910.1000 Table Z-1.

Notes:
 

 

Notes:
 

 

Notes:
 

 

Health factors:  See NIH-NLM PubChem. IDLH
Carcinogenic classifications: TLV-A4 Notes:
 

 

AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
 

 

Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Nitrapyrin

NIOSH: Pocket Guide to Chemical Hazards - 2-Chloro-6-trichloromethyl pyridine

Literature References

 
  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Nitrapyrin. See annual publication for most recent information.

Last Updated Date : 12/15/2020