CARBOFURAN

Chemical Identification
CAS #	1563-66-2
Formula	C₁₂H₁₅NO₃
Synonyms	2,3-dihydro-2,2-dimethyl-7-benzofuranyl methylcarbamate; Furacarb; Furadan

Physical Properties
Physical description	Odorless, white or grayish, crystalline solid.
Boiling point		Molecular weight	221.3
Freezing point/melting point	304°F	Vapor pressure	(77°F): 0.000003 mmHg
Flash point		Vapor density
Specific gravity	1.18	Ionization potential
Lower explosive limit (LEL)		Upper explosive limit (UEL)
NFPA health rating		NFPA fire rating
NFPA reactivity rating		NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs

Monitoring Methods Used by OSHA
Analyte code (IMIS no.)	0526
Sampling group
Sampler/Sampling media	OSHA versatile sampler (OVS-2) - 13 mm XAD-2 tube (270/140 mg) with GFF enclosed [SKC 226-30-16]
Sampling time^*
Sampling volume (TWA)^*	480 L
Sampling flow rate (TWA)^*	1 L/min
Sampling volume (STEL/Peak/C)^*
Sampling flow rate (STEL/Peak/C)^*
Analytical method instruments	HPLC-UV
Method reference	OSHA PV2127 (partially validated)
Notes
Special requirements

^* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Bulk/Wipe Method
Wipe Sampler/Sampling media	Wipe with Whatman 41. [WHA1441866]
Bulk Method	Limit the amount of bulk submitted to 1 g or 1 mL.

On-Site Screening Techniques
Device
Model/Type
Sampling information (see manufacturer instructions)

**Exposure Limits**
OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak		NIOSH REL Up to 10-hour TWA (ST) STEL (C) Ceiling		ACGIH TLV© 8-hour TWA (ST) STEL (C) Ceiling		CAL/OSHA PEL 8-hour TWA (ST) STEL (C) Ceiling Peak
PEL-TWA		REL-TWA	0.1 mg/m³	TLV-TWA	0.1 mg/m³ (inhalable fraction and vapor) [2001]	PEL-TWA	0.1 mg/m³
PEL-STEL		REL-STEL		TLV-STEL		PEL-STEL
PEL-C		REL-C		TLV-C		PEL-C
Skin notation	NA	Skin notation	N	Skin notation	N	Skin notation	N
Notes: Not established		Notes:		Notes: BEI®		Notes:
Health factors: See NIH-NLM PubChem.		IDLH
Carcinogenic classifications: TLV-A4		Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:

Additional Resources and Literature References

NOAA: CAMEO Chemicals - Carbofuran

NIOSH: Pocket Guide to Chemical Hazards - Carbofuran

Literature References

ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Carbofuran. See annual publication for most recent information.
FMC Corporation: Furadan® 4 F Insecticide/Nematicide . Material Safety Data Sheet. April 2003.
Huang, J., Zhang, S., Ding, M., Zhou, A., Zhang, J., Zhang, J.: Acute effects of carbofuran in workers of two pesticide plants. Med. Lav. 89(Suppl. 2): S105-111, 1998.
Jeon, S.D., Lim, J.S. and Moon, C.K.: Carbofuran suppresses T-cell-mediated immune responses by the suppression of T-cell responsiveness, the differential inhibition of cytokine production, and NO production in macrophages. Toxicol. Lett. 119(2): 143-155, 2001.
Pohanish, R.P. (editor): Carbofuran. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 486-488.
Yang, P.Y., Tsao, T.C., Lin, J.L., Lyu, R.K. and Chiang, P.C.: Carbofuran-induced delayed neuropathy. J. Toxicol. Clin. Toxicol. 38(1): 43-46, 2000.

Last Updated Date : 12/21/2020

CARBOFURAN

Chemical Identification

Physical Properties

Monitoring Methods Used by OSHA

Bulk/Wipe Method

On-Site Screening Techniques

Exposure Limits

Additional Resources and Literature References