ENFLURANE
| CAS # | 13838-16-9 |
|---|---|
| Formula |
CHF₂OCF₂CHClF |
| Synonyms |
2-chloro-1-(difluoromethoxy)-1,1,2-trifluoroethane; 2-chloro-1,1,2-trifluoroethyl difluoromethyl ether; ethrane |
| Physical description | Clear, colorless liquid with a mild, sweet odor. | ||
|---|---|---|---|
| Boiling point | 134°F | Molecular weight | 184.5 |
| Freezing point/melting point | Vapor pressure | 175 mmHg | |
| Flash point | Vapor density | ||
| Specific gravity | 1.52 at 77°F | Ionization potential | |
| Lower explosive limit (LEL) | Upper explosive limit (UEL) | ||
| NFPA health rating | NFPA fire rating | ||
| NFPA reactivity rating | NFPA special instruction | ||
| Vapor hazard ratio (VHR) | |||
| Historical exceedance percentage | |||
| Target organs | |||
| Analyte code (IMIS no.) | 1038 | 1038 |
|---|---|---|
| Sampling group | ||
| Sampler/Sampling media | Anasorb 747 (140/70 mg) [SKC 226-81A] | CSC tube (100/50 mg) [SKC 226-01] |
| Sampling time* |
|
|
| Sampling volume (TWA)* |
12 L |
10 L |
| Sampling flow rate (TWA)* |
0.05 L/min |
0.1 L/min |
| Sampling volume (STEL/Peak/C)* |
|
|
| Sampling flow rate (STEL/Peak/C)* |
|
|
| Analytical method instruments | GC-FID | GC-FID |
| Method reference | OSHA 103 (fully validated) | OSHA 29 (fully validated) |
| Notes |
|
|
| Special requirements |
|
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* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.
| Wipe Sampler/Sampling media |
|
|---|---|
| Bulk Method |
|
| Device | Infrared spectrophotometer | Infrared spectrophotometer | Organic vapor analyzer |
|---|---|---|---|
| Model/Type | Miran 1A & 1B | Miran 103 | |
|
Sampling information (see manufacturer instructions) |
0.03 ppm at 8.9 µm | 0-10 ppm at 8.7 µm |
|
OSHA PEL
8-hour TWA (ST) STEL (C) Ceiling Peak |
NIOSH REL
Up to 10-hour TWA (ST) STEL (C) Ceiling |
ACGIH TLV©
8-hour TWA (ST) STEL (C) Ceiling |
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|---|---|---|---|---|---|---|---|
| PEL-TWA |
|
REL-TWA |
|
TLV-TWA |
75 ppm [1979] |
PEL-TWA |
2 ppm (15 mg/m³) |
| PEL-STEL |
|
REL-STEL |
|
TLV-STEL |
|
PEL-STEL |
|
| PEL-C |
|
REL-C |
2 ppm (15.1 mg/m³) [60 minutes] |
TLV-C |
|
PEL-C |
|
| Skin notation |
NA |
Skin notation |
N |
Skin notation |
N |
Skin notation |
N |
|
Notes:
Not established |
Notes:
CEILING IS FOR EXPOSURE TO WASTE ANESTHETIC GASES |
Notes:
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Notes:
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| Health factors: See NIH-NLM PubChem. | IDLH | ||||||
| Carcinogenic classifications: IARC-3, TLV-A4 |
Notes:
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AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
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Additional Resources and Literature References
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NOAA: CAMEO Chemicals - Enflurane NIOSH: Pocket Guide to Chemical Hazards - Enflurane Literature References
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Last Updated Date : 12/28/2020