N-BUTYL LACTATE (BUTYL LACTATE)

Chemical Identification
Chemical Identification
CAS # 138-22-7
Formula

C₇H₁₄O₃

Synonyms
 

butyl ester of 2-hydroxypropanoic acid; butyl ester of lactic acid; butyl lactate

Physical Properties
Physical Properties
Physical description Clear, colorless to white liquid with a mild, transient odor.
Boiling point 370°F Molecular weight 146.2
Freezing point/melting point -45°F Vapor pressure 0.4 mmHg
Flash point 160°F Vapor density 5.04
Specific gravity 0.98 Ionization potential
Lower explosive limit (LEL) 1.15% Upper explosive limit (UEL)
NFPA health rating 1 NFPA fire rating 2
NFPA reactivity rating 0 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 0478
Sampling group
Sampler/Sampling media CSC tube (100/50 mg) [SKC 226-01]
Sampling time*
 

 

Sampling volume (TWA)*
 

10 L

Sampling flow rate (TWA)*
 

0.2 L/min

Sampling volume (STEL/Peak/C)*
 

 

Sampling flow rate (STEL/Peak/C)*
 

 

Analytical method instruments GC-FID
Method reference OSHA PV2080 (partially validated)
Notes
 

Keep samples refrigerated when not in transit. Ship samples overnight with cold-packs as soon as possible.

Special requirements
 

 

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
 

 

Bulk Method
Bulk Method
 

 

On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA
 

 

REL-TWA
 

5 ppm (25 mg/m³)

TLV-TWA
 

5 ppm [1973]

PEL-TWA
 

5 ppm (25 mg/m³)

PEL-STEL
 

 

REL-STEL
 

 

TLV-STEL
 

 

PEL-STEL
 

 

PEL-C
 

 

REL-C
 

 

TLV-C
 

 

PEL-C
 

 

Skin notation
 

N

Skin notation
 

N

Skin notation
 

N

Skin notation
 

N

Notes:
 

Not established

Notes:
 

 

Notes:
 

 

Notes:
 

 

Health factors:  See NIH-NLM PubChem. IDLH
Carcinogenic classifications: Not listed Notes:
 

 

AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
 

 

Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Butyl lactate

NIOSH: Pocket Guide to Chemical Hazards - n-Butyl lactate

Literature References

 
  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - n-Butyl lactate. See annual publication for most recent information.
  • Clary, J.J., Feron, V.J. and van Velthuijsen, J.A.: Safety assessment of lactate esters. Regul. Toxicol. Pharmacol. 27(2): 88-97, 1998.
  • Pohanish, R.P. (editor): Butyl Lactate. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 416-418.
  • Teeguarden, J.G., et al.: Derivation of a human equivalent concentration for n-butanol using a physiologically based pharmacokinetic model for n-butyl acetate and metabolites n-butanol and n-butyric acid. Toxicol. Sci. 85(1): 429-446, 2005.

Last Updated Date : 01/05/2021