ISOAMYL ALCOHOL†

Chemical Identification
Chemical Identification
CAS # 123-51-3
Formula

C₅H₁₂O

Synonyms

fermentation amyl alcohol; fusel oil; isobutyl carbinol; isopentyl alcohol; 3-methyl-1-butanol; primary isoamyl alcohol

Physical Properties
Physical Properties
Physical description Colorless liquid with a disagreeable odor.
Boiling point 270°F Molecular weight 88.15
Freezing point/melting point -179°F Vapor pressure 28 mmHg
Flash point 114°F Vapor density
Specific gravity 0.81 at 68°F Ionization potential
Lower explosive limit (LEL) 1.2% at 212°F Upper explosive limit (UEL) 9% at 212°F
NFPA health rating 1 NFPA fire rating 2
NFPA reactivity rating 0 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 1532
Sampling group
Sampler/Sampling media CSC tube (100/50 mg) [SKC 226-01]
Sampling time*
Sampling volume (TWA)*

1-10 L

Sampling flow rate (TWA)*

0.01-0.2 L/min

Sampling volume (STEL/Peak/C)*
Sampling flow rate (STEL/Peak/C)*
Analytical method instruments GC-FID
Method reference NIOSH 1402 (partially validated)
Notes
Special requirements

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
Bulk Method
Bulk Method
On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA

100 ppm (360 mg/m³)

REL-TWA

100 ppm (360 mg/m³)

TLV-TWA

100 ppm [1990]

PEL-TWA

100 ppm (360 mg/m³)

PEL-STEL REL-STEL

125 ppm (450 mg/m³)

TLV-STEL

125 ppm [1990]

PEL-STEL

125 ppm (450 mg/m³)

PEL-C REL-C TLV-C PEL-C
Skin notation

N

Skin notation

N

Skin notation

N

Skin notation

N

Notes:

See 29 CFR 1910.1000 Table Z-1.

Notes: Notes: Notes:
Health factors:  See NIH-NLM PubChem. IDLH

500 ppm

Carcinogenic classifications: Not listed Notes:
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Isoamyl alcohol

NIOSH: Pocket Guide to Chemical Hazards - Isoamyl alcohol (primary)

Literature References

  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Isoamyl alcohol. See annual publication for most recent information.
  • International Chemical Safety Cards (WHO/IPCS/ILO): Isoamyl alcohol.
  • Klimisch, H.-J. and Hellwig, J.: Studies on the prenatal toxicity of 3-methyl-1-butanol and 2-methyl-1-propanol in rats and rabbits following inhalation exposure. Fundam. Appl. Toxicol. 27(1): 77-89, 1995.
  • Pohanish, R.P. (editor): Isoamyl Alcohol. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 2. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 1320-1322.

Last Updated Date : 12/31/2020