MALATHION†

Chemical Identification
Chemical Identification
CAS # 121-75-5
Formula

C₁₀H₁₉O₆PS₂

Synonyms

S-[1,2-bis(ethoxycarbonyl) ethyl]O,O-dimethyl-phosphorodithioate; diethyl (dimethoxyphosphinothioylthio) succinate

Physical Properties
Physical Properties
Physical description Deep-brown to yellow liquid with a garlic-like odor.
Boiling point 140°F (decomposes) Molecular weight 330.4
Freezing point/melting point 37.1°F Vapor pressure 0.00004 mmHg
Flash point >325°F (open-cup) Vapor density
Specific gravity 1.234 at 77°F Ionization potential
Lower explosive limit (LEL) Upper explosive limit (UEL)
NFPA health rating NFPA fire rating
NFPA reactivity rating NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 1616
Sampling group
Sampler/Sampling media OSHA versatile sampler (OVS-2) - 13 mm XAD-2 tube (270/140 mg) with GFF enclosed [SKC 226-30-16]
Sampling time*

60 min

Sampling volume (TWA)*

60 L

Sampling flow rate (TWA)*

1 L/min

Sampling volume (STEL/Peak/C)*

15 L

Sampling flow rate (STEL/Peak/C)*

1 L/min

Analytical method instruments GC-FPD
Method reference OSHA 62 (fully validated)
Notes
Special requirements
 

 

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
 

Wipe with GFF (37 mm), Type A/E [AP4003705]

Bulk Method
Bulk Method
 

Limit the amount of bulk submitted to 1 g or 1 mL.

On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA
 

15 mg/m³ (total dust)

REL-TWA
 
 

10 mg/m³

TLV-TWA
 
 

1 mg/m³ (inhalable fraction and vapor) [2000]

PEL-TWA
 
 

10 mg/m³

PEL-STEL
 

 

REL-STEL
 
 

 

TLV-STEL
 
 

 

PEL-STEL
 
 

 

PEL-C
 

 

REL-C
 
 

 

TLV-C
 
 

 

PEL-C
 
 

 

Skin notation
 
 

Y

Skin notation
 
 

Y

Skin notation
 
 

Y

Skin notation
 
 

Y

Notes:
 
 

See 29 CFR 1910.1000 Table Z-1.

Notes:
 
 

 

Notes:
 
 

BEI®

Notes:
 
 

 

Health factors:  See NIH-NLM PubChem. IDLH
 
 

250 mg/m³

Carcinogenic classifications: IARC-3, TLV-A4 Notes:
 
 

 

AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
 
 

 

Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Malathion

NIOSH: Pocket Guide to Chemical Hazards - Malathion

Literature References

 
 
  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - Malathion. See annual publication for most recent information.
  • Bouchard, M, Gosselin, N.H., Brunet, R.C., Samuel, O., Dumoulin, M.-J. and Carrier, G.: A toxicokinetic model of malathion and its metabolites as a tool to assess human exposure and risk through measurements of urinary biomarkers. Toxicol. Sci. 73(1): 182-194, 2003.
  • Pohanish, R.P. (editor): Malathion. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 2. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 1433-1436.

Last Updated Date : 01/28/2021