2-METHOXYETHYL ACETATE (METHYL CELLOSOLVE ACETATE; ETHYLENE GLYCOL METHYL ACETATE)†

Chemical Identification
Chemical Identification
CAS # 110-49-6
Formula

C₅H₁₀O₃

Synonyms

ethylene glycol monomethyl ether acetate; EGMEA; glycol monomethyl ether acetate; Methyl Cellosolve® acetate; 2-methoxyethyl acetate

Physical Properties
Physical Properties
Physical description Colorless liquid with a mild, ether-like odor.
Boiling point 293°F Molecular weight 118.13
Freezing point/melting point -85°F Vapor pressure 2 mmHg
Flash point 120°F Vapor density 4.07
Specific gravity 1.006 Ionization potential
Lower explosive limit (LEL) 1.7% Upper explosive limit (UEL) 8.2%
NFPA health rating 2 NFPA fire rating 2
NFPA reactivity rating 0 NFPA special instruction
Vapor hazard ratio (VHR)
Historical exceedance percentage
Target organs
Monitoring Methods Used by OSHA
Monitoring Methods Used by OSHA
Analyte code (IMIS no.) 1170
Sampling group
Sampler/Sampling media CSC tube (100/50 mg) [SKC 226-01]
Sampling time*
Sampling volume (TWA)*

10 L

Sampling flow rate (TWA)*

0.1 L/min

Sampling volume (STEL/Peak/C)*
Sampling flow rate (STEL/Peak/C)*
Analytical method instruments GC-FID
Method reference OSHA 53 (fully validated)
Notes
 

Samples for 2-methoxyethyl acetate and/or for 2-ethoxyethyl acetate should be refrigerated upon receipt at the analytical laboratory.

Special requirements
 

 

* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.

Wipe Method
Wipe Method
Sampler/Sampling media
 

Wipe with charcoal pad, seal in glass vial for shipment. [3M 3500]

Bulk Method
Bulk Method
 

 

On-Site Screening Techniques
On-Site Screening Techniques
Device
Model/Type
Sampling information
(see manufacturer instructions)
Exposure Limits
Exposure Limits
OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
NIOSH REL
Up to 10-hour TWA
(ST) STEL
(C) Ceiling
ACGIH TLV©
8-hour TWA
(ST) STEL
(C) Ceiling
CAL/OSHA PEL
8-hour TWA
(ST) STEL
(C) Ceiling
Peak
PEL-TWA
 

25 ppm (120 mg/m³)

REL-TWA
 

0.1 ppm (0.5 mg/m³)

TLV-TWA
 

0.1 ppm [2005]

PEL-TWA
 

5 ppm (24 mg/m³)

PEL-STEL
 

 

REL-STEL
 

 

TLV-STEL
 

 

PEL-STEL
 

 

PEL-C
 

 

REL-C
 

 

TLV-C
 

 

PEL-C
 

 

Skin notation
 

Y

Skin notation
 

Y

Skin notation
 

Y

Skin notation
 

N

Notes:
 

See 29 CFR 1910.1000 Table Z-1.

Notes:
 

 

Notes:
 

BEI®

Notes:
 

 

Health factors:  See NIH-NLM PubChem. IDLH
 

200 ppm

Carcinogenic classifications: Not listed Notes:
 

 

AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
 

 

Additional Resources and Literature References
Additional Resources and Literature References

NOAA: CAMEO Chemicals - Ethylene glycol monomethyl ether acetate

NIOSH: Pocket Guide to Chemical Hazards - Methyl Cellosolve acetate

Literature References

 
  • ACGIH: Documentation of the Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) - 2-Methoxyethyl acetate. See annual publication for most recent information.
  • Johanson, G.: Toxicity review of ethylene glycol monomethyl ether and its acetate ester. Crit. Rev. Toxicol. 30(3): 307-345, 2000.
  • Pohanish, R.P. (editor): Methoxyethyl Acetate. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 2. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 1507-1509.

Last Updated Date : 12/15/2020