Lapse in Appropriations
For workplace safety and health, please call 800-321-6742; for mine safety and health, please call 800-746-1553; for Job Corps, please call 800-733-5627 and for Wage and Hour, please call 866-487-9243 (866-4-US-WAGE). This website is currently not being updated due to the suspension of Federal government services. The last update to the site was 10/1/2025. Updates to the site will start again when the Federal government resumes operations.
2-METHOXYETHYL ACETATE (METHYL CELLOSOLVE ACETATE; ETHYLENE GLYCOL METHYL ACETATE)†
| CAS # | 110-49-6 |
|---|---|
| Formula |
C₅H₁₀O₃ |
| Synonyms |
ethylene glycol monomethyl ether acetate; EGMEA; glycol monomethyl ether acetate; Methyl Cellosolve® acetate; 2-methoxyethyl acetate |
| Physical description | Colorless liquid with a mild, ether-like odor. | ||
|---|---|---|---|
| Boiling point | 293°F | Molecular weight | 118.13 |
| Freezing point/melting point | -85°F | Vapor pressure | 5 mmHg |
| Flash point | 120°F | Vapor density | 4.07 |
| Specific gravity | 1.006 | Ionization potential | |
| Lower explosive limit (LEL) | 1.7% | Upper explosive limit (UEL) | 8.2% |
| NFPA health rating | 2 | NFPA fire rating | 2 |
| NFPA reactivity rating | 0 | NFPA special instruction | |
| Vapor hazard ratio (VHR) | |||
| Historical exceedance percentage | |||
| Target organs | |||
| Analyte code (IMIS no.) | 1170 |
|---|---|
| Sampling group | |
| Sampler/Sampling media | CSC tube (100/50 mg) [SKC 226-01] |
| Sampling time* | |
| Sampling volume (TWA)* | 10 L |
| Sampling flow rate (TWA)* | 0.1 L/min |
| Sampling volume (STEL/Peak/C)* | |
| Sampling flow rate (STEL/Peak/C)* | |
| Analytical method instruments | GC-FID |
| Method reference | OSHA 53 (fully validated) |
| Notes |
Keep samples refrigerated when not in transit. Ship samples overnight with cold-packs as soon as possible. |
| Special requirements |
|
* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.
| Wipe Sampler/Sampling media |
Wipe with charcoal pad, seal in glass vial for shipment. [3M 3500] |
|---|---|
| Bulk Method |
|
| Device | |||||
|---|---|---|---|---|---|
| Model/Type | |||||
|
Sampling information (see manufacturer instructions) |
|
OSHA PEL
8-hour TWA (ST) STEL (C) Ceiling Peak |
NIOSH REL
Up to 10-hour TWA (ST) STEL (C) Ceiling |
ACGIH TLV©
8-hour TWA (ST) STEL (C) Ceiling |
|||||
|---|---|---|---|---|---|---|---|
| PEL-TWA |
25 ppm (120 mg/m³) |
REL-TWA |
0.1 ppm (0.5 mg/m³) |
TLV-TWA |
0.1 ppm [2005] |
PEL-TWA |
5 ppm (24 mg/m³) |
| PEL-STEL |
|
REL-STEL |
|
TLV-STEL |
|
PEL-STEL |
|
| PEL-C |
|
REL-C |
|
TLV-C |
|
PEL-C |
|
| Skin notation |
Y |
Skin notation |
Y |
Skin notation |
Y |
Skin notation |
N |
| Notes: |
Notes:
|
Notes:
BEI® |
Notes:
|
||||
| Health factors: See NIH-NLM PubChem. | IDLH |
200 ppm |
|||||
| Carcinogenic classifications: Not listed |
Notes:
|
||||||
|
AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3:
|
|||||||
Additional Resources and Literature References
|
NOAA: CAMEO Chemicals - Ethylene glycol monomethyl ether acetate NIOSH: Pocket Guide to Chemical Hazards - Methyl Cellosolve acetate Literature References
|
Last Updated Date : 09/22/2022