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Chemical Sampling Information (CSI)
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General Description

Synonyms: 2,4,5-Trichlorophenoxyacetic Acid

OSHA IMIS Code Number: 2324

Chemical Abstracts Service (CAS) Registry Number: 93-76-5

NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: AJ8400000; 2823

Department of Transportation Regulation Number (49 CFR 172.101) and Guide: 2765 152; UN2765

NIOSH Pocket Guide to Chemical Hazards, 2,4,5-T : chemical description, physical properties, potentially hazardous incompatibilities, and more

Chemical Description and Physical Properties:
colorless to tan, odorless solid
molecular weight: 256
boiling point: Decomposes
vapor pressure: approx. 0 mm
melting point: 316 F
Incompatibilities: None hazardous

Exposure Limits

OSHA Permissible Exposure Limit (PEL):
General Industry: 10 mg/m3
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 10 mg/m3 TWA; Appendix A4 (Not Classifiable as a Human Carcinogen)

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 10 mg/m3 TWA

Health Factors

Carcinogenic Classification:
International Agency for Research on Cancer (IARC): Group 2B, possibly carcinogenic to humans (Chlorophenoxy Herbicides) [63 KB PDF, 23 pages]
Potential Symptoms: Animal studies: ataxia, skin irritation, acne-like rash

Health Effects: Suspect teratogen (HE5); Mutagen (HE2)

Affected Organs: Skin, liver, GI tract
Monitoring Methods used by OSHA

Laboratory Sampling/Analytical Method:
  • sampling media: Glass Fiber Filter (Gelman Type AE or equivalent)
    maximum volume: 200 Liters
    maximum flow rate: 3.0 L/min
    current analytical method: High Performance Liquid Chromatography; HPLC/UL51.
    method reference: 1, 2 (OSHA modified NIOSH 5001)
    sampling and analytical error: 0.09
    method classification: Fully Validated
Conditions: Column: C18 Mobile Phase: 65:35:0.1 Methanol:Water:H3PO4 Detector Wavelength: 289 nm Detection Limit:

Wipe Sampling Method: Yes, with Whatman 42 filter.

Bulk Method: Limit the amount of bulk submitted to one gram or one mL.

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Page last updated: 01/15/1999

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