NAME: Nicotine
SYNONYM(s): 3-(1-Methyl-2-pyrrolidyl) pyridine
IMIS: 1855
CAS: 54-11-5
NIOSH: RTECS QS5250000; 51804
DOT: UN1654 Poison
DESCRIPTION:
Pale yellow to dark brown liquid with a slight, fishy odor when warm.
MW: 162
BP: 511 F
VP: 0.0425 mm
MP: -110 F
INCOM: Strong oxidizers, strong acids
Exposure Limits
OSHA GENERAL INDUSTRY PEL: 0.5 mg/m3 TWA (Skin)
OSHA CONSTRUCTION INDUSTRY PEL: 0.5 mg/m3 TWA (Skin)
ACGIH TLV: 0.5 mg/m3 TWA (Skin)
NIOSH REL: 0.5 mg/m3 TWA (Skin)
Health Factors
SYMPTOM(s): Salivation; nausea, abdominal pain, vomiting, diarrhea; headaches, dizziness; disturbed hearing, vision; confusion, weakness, incoordination; paroxysmal atrial fibrillation; convulsions; dypsnea
HEALTH EFFECTS: Acute systemic toxicity (HE4); CNS damage (HE7) Suspect teratogen (HE5)
ORGAN: CNS, CVS, lungs, GI tract
Monitoring
PRIMARY SAMPLING/ANALYTICAL METHOD (SLC1):
MEDIA: XAD-4 Tube (80/40 mg sections)
MAX V: 100 Liters MAX F: 1.0 L/min
ANL 1: Gas Chromatography; GC/NPD
REF: 1 (NIOSH 2544)
SAE: 0.11
CLASS: Fully Validated
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