Chemical Sampling Information
	Nickel, Metal and Insoluble compounds (as Ni)
Quick Links General Description Exposure Limits Health Factors Monitoring Search    [use word(s)/phrase] Table of Contents By Name A B C D E F G H I J K L M N O P Q R S T U V W X Y Z By CAS Number General Description Synonyms: Nickel metal: Elemental nickel, Nickel catalyst; Nickel subsulfide; Other synonyms vary depending upon the specific nickel compound OSHA IMIS Code Number: 1840 Chemical Abstracts Service (CAS) Registry Number: 7440-02-0 Other Chemical Abstracts Service (CAS) Registry Number: 12035-72-2 (Nickel subsulfide) NIOSH, Registry of Toxic Effects (RTECS) Identification Number: QR5950000 NIOSH Pocket Guide to Chemical Hazards, Nickel metal and other compounds (as Ni): chemical description, physical properties, potentially hazardous incompatibilities, and more Exposure Limits OSHA Permissible Exposure Limit (PEL) for General Industry: 29 CFR 1910.1000 Z-1 Table -- 1 mg/m3 TWA (Does not apply to Nickel Carbonyl) OSHA Permissible Exposure Limit (PEL) for Construction Industry: 29 CFR 1926.55 Appendix A -- 1 mg/m3 TWA (Does not apply to Nickel Carbonyl) OSHA Permissible Exposure Limit (PEL) for Maritime: 29 CFR 1915.1000 Table Z-Shipyards -- 1 mg/m3 TWA (Does not apply to Nickel Carbonyl) American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): Elemental - 1.5 mg/m3 TWA, Inhalable fraction*, Appendix A5 - Not Suspected as a Human Carcinogen; insoluble inorganic compounds (NOS) - 0.2 mg/m3 TWA, Inhalable fraction*, Appendix A1 - Confirmed Human Carcinogen; Nickel subsulfide - 0.1 mg/m3 TWA, Inhalable fraction*, Appendix A1 - Confirmed Human Carcinogen * - see Appendix C, paragraph A [TLVs listed under Nickel, as Ni] National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 0.015 mg/m3 TWA ; Appendix A - NIOSH Potential Occupational Carcinogens; (This REL does not apply to Nickel carbonyl) Health Factors International Agency for Research on Cancer (IARC) carcinogenic classification: Metallic Nickel - Group 2B, possibly carcinogenic to humans; Nickel Compounds - Group 1, carcinogenic to humans. [82 KB, PDF] NIOSH Immediately Dangerous To Life or Health Concentration (IDLH): 10 mg/m3 (as Ni) Potential symptoms: Sensitization dermatitis, allergic asthma, cough, shortness of breath, pneumonitis; decreased sense of smell [potential occupational carcinogen] Health Effects: Respiratory sensitization (asthma) (HE9); Cumulative lung damage (HE10); Dermatitis (HE3) Affected organs: Nasal cavities, lungs, skin Notes: OSHA Select Carcinogen. Most cases of sinonasal cancer associated with nickel exposure have occurred in nickel refinery workers, although a few have been reported in alkaline battery and cutlery workers. Nickel exposure has been associated with work-related respiratory symptoms in welders. Date Last Revised: 06/24/2004 Literature Basis: NIOSH Pocket Guide to Chemical Hazards: Nickel metal and other compounds (as Ni). International Chemical Safety Cards (WHO/IPCS/ILO): Nickel. EPA Air Toxics Website: Nickel Compounds. U.S. Environmental Protection Agency Technology Transfer Network. Fishwick, D., Bradshaw, L., Slater, T., Curran, A. and Pearce, N.: Respiratory symptoms and lung function change in welders: are they associated with workplace exposures? N. Z. Med. J. 117(1193): U872, 2004. Pohanish, R.P. (editor): Nickel and Soluble Compounds. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 2. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 1666-1669. Sunderman, F.W., Jr.: Nasal toxicity, carcinogenicity, and olfactory uptake of metals. Ann. Clin. Lab. Sci. 31(1): 3-24, 2001. Monitoring Methods used by OSHA Laboratory Sampling/Analytical Method: sampling media: Mixed Cellulose Ester Filter (MCEF) 0.8 microns maximum volume: 960 Liters   minimum volume: 480 Liters   maximum flow rate: 2.0 L/min current analytical method: Atomic Absorption Spectroscopy; AAS method reference: OSHA Analytical Method (OSHA ID-121) method classification: Fully Validated alternate analytical method: Inductively Coupled Argon Plasma; ICP-AES/MS method reference: OSHA Analytical Method (OSHA ID-125G, OSHA 1006) method classification: Fully Validated note: If the filter is not overloaded, samples may be collected up to an 8-hour period. All Trademarks are the property of their respective owners. Accessibility Assistance: Contact the OSHA Directorate of Technical Support and Emergency Management at 202-693-2300 for assistance accessing PDF materials.