NAME: 4-Aminodiphenyl
SYNONYM(s): p-Aminodiphenyl; 4-Aminobiphenyl
IMIS: 0162
CAS: 92-67-1
NIOSH: RTECS DU8925000; 20613
DESCRIPTION:
Colorless crystals which turn purple on contact with air; floral odor.
MW: 169
BP: 575 F
MP: 127 F
Exposure Limits
OSHA GENERAL INDUSTRY PEL: Cancer-Suspect Agent 29 CFR 1910.1011
ACGIH TLV: Appendix A1 (Confirmed Human Carcinogen)
NIOSH REL: 29 CFR 1910.1011 Potential Carcinogen
Health Factors
NTP: Human Carcinogen
IARC: Group 1, carcinogenic to humans (4-Aminobiphenyl)
SYMPTOM(s): Headaches, lethargy, dizziness; dyspnea; ataxia, weakness; methemoglobinemia; urinary burning; acute hemorrhage cystitis, (carcinogenic)
HEALTH EFFECTS: Cancer---Currently regulated by OSHA as carcinogen; chiefly work practice standards (HE1) LD50 (oral, rat) 500 mg/kg; SKIN ABS: Yes
ORGAN: Bladder, skin
Monitoring
PRIMARY SAMPLING/ANALYTICAL METHOD (SLC1):
MEDIA: Coated Glass Fiber Filters (37 mm) in 3 piece cassette. Coating is Sulfuric Acid.
MAX V: 100 Liters MAX F: 1.0 L/min
ANL 1: Gas Chromatography; GC/ECD
REF: 2 (OSHA 93)
SAE: 0.09
CLASS: Fully Validated
NOTE: Within ten hours after sampling, transfer filter to glass vial containing 2 mL deionized water. Filters may be obtained by OSHA personnel from SLTC.
COND: C18 column; 65% methanol 35% water; UV Det: 280, 220; Fluor. ex. 265; Em 389; Retention time, 8.9 min; DL 0.06 ug/sample; C/P JRL 12/78
WIPE:
Yes, with Glass Fiber Filter.
BULK METHOD:
Limit the amount of bulk submitted to one gram or one mL.
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