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DIMETHYL SULFATE†
| CAS # | 77-78-1 |
|---|---|
| Formula |
C₂H₆O₄S |
| Synonyms |
dimethyl ester of sulfuric acid; dimethylsulfate; methyl sulfate |
| Physical description | Colorless, oily liquid with a faint, onion-like odor. | ||
|---|---|---|---|
| Boiling point | 370°F (decomposes) | Molecular weight | 126.1 |
| Freezing point/melting point | -25°F | Vapor pressure | 0.1 mmHg |
| Flash point | 182°F | Vapor density | |
| Specific gravity | 1.33 | Ionization potential | |
| Lower explosive limit (LEL) | Upper explosive limit (UEL) | ||
| NFPA health rating | 4 | NFPA fire rating | 2 |
| NFPA reactivity rating | 1 | NFPA special instruction | |
| Vapor hazard ratio (VHR) | |||
| Historical exceedance percentage | |||
| Target organs | |||
| Analyte code (IMIS no.) | 0960 |
|---|---|
| Sampling group | |
| Sampler/Sampling media | Porapak Q tube (150/75 mg) [SKC 226-115] |
| Sampling time* | |
| Sampling volume (TWA)* | 10 L |
| Sampling flow rate (TWA)* | 0.1 L/min |
| Sampling volume (STEL/Peak/C)* | |
| Sampling flow rate (STEL/Peak/C)* | |
| Analytical method instruments | GC-FPD |
| Method reference | OSHA PV2147 (partially validated) |
| Notes | |
| Special requirements |
* All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details.
| Wipe Sampler/Sampling media | |
|---|---|
| Bulk Method |
| Device | Detector tube |
|---|---|
| Model/Type | Dräger - Dimethyl Sulfate 0.005/c, 6718701 |
|
Sampling information (see manufacturer instructions) |
200 strokes, 0.005-0.05 ppm range, uncertainty approx 50% |
|
OSHA PEL
8-hour TWA (ST) STEL (C) Ceiling Peak |
NIOSH REL
Up to 10-hour TWA (ST) STEL (C) Ceiling |
ACGIH TLV©
8-hour TWA (ST) STEL (C) Ceiling |
|||||
|---|---|---|---|---|---|---|---|
| PEL-TWA |
1 ppm (5 mg/m³) |
REL-TWA |
0.1 ppm (0.5 mg/m³) |
TLV-TWA |
0.1 ppm [1985] |
PEL-TWA |
0.1 ppm (0.5 mg/m³) |
| PEL-STEL | REL-STEL | TLV-STEL | PEL-STEL | ||||
| PEL-C | REL-C | TLV-C | PEL-C | ||||
| Skin notation |
Y |
Skin notation |
Y |
Skin notation |
Y |
Skin notation |
Y |
| Notes: |
Notes:
CARCINOGEN (Ca): REDUCE EXPOSURE TO LOWEST FEASIBLE CONCENTRATION. See Appendix A |
Notes: | Notes: | ||||
| Health factors: See NIH-NLM PubChem. | IDLH |
7 ppm |
|||||
| Carcinogenic classifications: IARC-2A, NOSH-Ca, NTP-R, TLV-A3, EPA-B2 |
Notes:
Ca |
||||||
| AIHA emergency response planning guidelines - ERPG-1/ERPG-2/ERPG-3: | |||||||
Additional Resources and Literature References
|
NOAA: CAMEO Chemicals - Dimethyl sulfate NIOSH: Pocket Guide to Chemical Hazards - Dimethyl sulfate Literature References
|
Last Updated Date : 12/28/2020