o-Tolidine Based Dye
- Synonyms: 4,4'-Diamino-3,3'-dimethylbiphenyl; Diaminoditolyl; 3,3'-Dimethylbenzidine; 3,3'-Dimethyl-4,4'-diphenyldiamine; 3,3'-Tolidine
- OSHA IMIS Code Number: T169
- Chemical Abstracts Service (CAS) Registry Number: 119-93-7
- NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: DD1225000; 14667
- NIOSH Pocket Guide to Chemical Hazards, o-Tolidine: Chemical description, physical properties, potentially hazardous incompatibilities, and more
- Carcinogenic Classificaiton:
- International Agency for Research on Cancer (IARC): Group 2B, possibly carcinogenic to humans (3,3'-Dimethylbenzidine and 3,3'-dimethylbenzidine-based dyes) (PDF)
- National Toxicology Program (NTP): Reasonably anticipated to be a human carcinogen (3,3'- Dimethylbenzidine and Dyes Metabolized to 3,3'-Dimethlybenzidine) (PDF)
Monitoring Methods used by OSHA
Primary Laboratory Sampling/Analytical Method (SLC1):
- Polytetrafluoroethylene Filter 5 micron
- maximum volume: 500 Liters
- maximum flow rate: 2.0 L/min
- current analytical method: High Performance Liquid Chromatography; HPLC/UL51
- method reference: 1 (NIOSH 5013 (PDF))
- method classification: Partially Validated
Wipe Sampling Method:
- Glass Fiber Filter
- Protect samples from heat and light. This method does not differentiate between different o-Toliding based dyes. For any dye analysis, a bulk sample of the dye must be sent to the Salt Lake Technical Center (SLTC). Limit the amount of bulk submitted to one gram or one mL.
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