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Chemical Sampling Information (CSI)
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General Description

Synonyms: bis-(Dimethylthiocarbamoyl)disulfide; Tetramethylthiuram disulfide; TMTD

OSHA IMIS Code Number: 2427

Chemical Abstracts Service (CAS) Registry Number: 137-26-8

NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: JO1400000; 32334

Department of Transportation Regulation Number (49 CFR 172.101) and Guide: NA 2771 151

NIOSH Pocket Guide to Chemical Hazards, Thiram: Chemical description, physical properties, potentially hazardous incompatibilities, and more

Chemical Description and Physical Properties:
colorless to cream solid (some commercial products dyed blue)
molecular weight: 240
boiling point: Decomposes
vapor pressure: approx. 0 mm
melting point: 155-156°C

Incompatibilities: Strong oxidizers and acids, oxidizable materials

Exposure Limits

OSHA Permissible Exposure Limit (PEL):
General Industry: 5 mg/m3

Construction Industry: 5 mg/m3 TWA
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 1 mg/m3 TWA

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 5 mg/m3 TWA


Health Factors

Carcinogenic Classification:
International Agency for Research on Cancer (IARC): Group 3, not classifiable as to its carcinogenicity to humans [1 MB PDF, 20 pages]
Potential Symptoms: Mucous membrane irritation; dermatitis; with ethanol consumption: flush, erythema, pruritis, urticaria; headaches; nausea, vomiting, diarrhea; weakness, dizziness, dyspnea

Health Effects: Acute systemic toxicity (Antabuse-like effects) (HE4) Suspect teratogen (HE5); Mutagen (HE2)

Affected Organs: Respiratory system, skin

Monitoring Methods used by OSHA

Primary Laboratory Sampling/Analytical Method (SLC1):
  • sampling media: Polytetrafluoroethylene (FA) filter 1.0 micron
    maximum flow rate: 3.0 L/min
    current analytical method: High Performance Liquid Chromatography; HPLC/UV
    method reference: 1 (NIOSH 5005) [18 KB PDF, 3 pages]
    method classification: Fully Validated
Conditions: Column: C18 Mobile Phase: 60:40 Acetonitrile: Water Detector Wavelength: 254 nm Detection Limit

Bulk Method: Limit the amount of bulk submitted to one gram or one mL.

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Page last updated: 02/27/2002

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