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Chemical Sampling Information (CSI)
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General Description

Synonyms: TMSN

OSHA IMIS Code Number: 2380

Chemical Abstracts Service (CAS) Registry Number: 3333-52-6

NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: WN4025000; 79460

NIOSH Pocket Guide to Chemical Hazards, Tetramethyl Succinonitrile: chemical description, physical properties, potentially hazardous incompatibilities, and more

Chemical Description and Physical Properties:
colorless, odorless solid
molecular weight: 136
boiling point: Sublimes
melting point: 338°F
Incompatibilities: Strong oxidizers

Exposure Limits

OSHA Permissible Exposure Limit (PEL):
General Industry: 0.5 ppm, 3 mg/m3 (Skin)

Construction Industry: 0.5 ppm, 3 mg/m3 TWA (Skin)
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 0.5 ppm, 2.8 mg/m3 TWA (Skin)

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 0.5 ppm TWA (Skin)


Health Factors

Potential Symptoms: Headaches; nausea; convulsions; coma

Health Effects: Acute systemic toxicity (CNS)-Headache, nausea, convulsions (HE4)

Affected Organs: CNS

Monitoring Methods used by OSHA

Primary Laboratory Sampling/Analytical Method (SLC1):
  • sampling media: Charcoal Tube (100/50 mg sections, 20/40 mesh)
    analytical solvent: Carbon Disulfide
    maximum volume: 48 Liters
    maximum flow rate: 0.2 L/min
    current analytical method: Gas Chromatography; GC/FID
    method reference: 1 (NIOSH S-155)
    sampling and analytical error: 0.12
    method classification: Partially Validated
Wipe Sampling Method: Wipe with charcoal pad, seal in glass vial for shipment.

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Page last updated: 05/19/2000