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N-Phenyl-2-Naphthylamine

General Description

  • Synonyms: N-Phenyl-beta-Naphthylamine
  • OSHA IMIS Code Number: N606
  • Chemical Abstracts Service (CAS) Registry Number: 135-88-6

Exposure Limits

  • American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): A2 (Suspected Human Carcinogen)
  • National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): Potential carcinogen

Health Factors

Carcinogenic Classification:

    • International Agency for Research on Cancer (IARC): Group 3, not classifiable as to its carcinogenicity to humans

Health Effects: Metabolizes to beta-Napthylamine in humans and animals

Monitoring Methods used by OSHA

Primary Laboratory Sampling/Analytical Method (SLC1):
  • Two coated, 25mm, extra thick glass fiber filters enclosed in a 3 piece opaque cassette. Coating is 10 mg vitamin C.
  • analytical solvent: Methanol
  • maximum volume: 240 Liters
  • maximum flow rate: 1.0 L/min
  • current analytical method: High Performance Liquid Chromatography; HPLC/FLU
  • method reference: 2 (OSHA 96)
  • sampling and analytical error: 0.09
  • method classification: Fully Validated

Conditions: Column: Radial-Pak C18 Mobile Phase: 85/15 Methanol Water Detector: 300nm Excitation, 370nm Emission Detection Limit: 32.5 pg/injection

Wipe Sampling Method:
  • Glass Fiber Filter
Bulk Method:
  • current analytical method: High performance liquid chromatography; HPLC/UV/Fluorescence
  • method reference: 2 (OSHA In-House File)
  • method classification: Not Validated
  • note: Limit the amount of bulk submitted to one gram or one mL.

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