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Chemical Sampling Information (CSI)
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General Description

Synonyms: N-[[(Methylamino)carbonyl]oxy]ethanimidothioic Acid Methyl Ester; Nudrin; Lannate

OSHA IMIS Code Number: 1644

Chemical Abstracts Service (CAS) Registry Number: 16752-77-5

NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: AK2975000; 2876

Chemical Description and Physical Properties:

solid
melting point: 78-79°C

Exposure Limits

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 2.5 mg/m3 TWA; Appendix A4 (Not Classifiable as a Human Carcinogen)

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 2.5 mg/m3 TWA

Health Factors

Health Effects: Cholinesterase inhibition (HE6) Mutagen (HE2); LD50 (oral, rat) 17 mg/kg

Monitoring Methods used by OSHA

Primary Laboratory Sampling/Analytical Method (SLC1):

  • sampling media: OSHA Versatile Sampler (OVS-2) - 13 mm XAD-2 tube (270/140 mg sections, 20/60 mesh) with Glass Fiber Filter enclosed
    analytical solvent: Acetonitrile
    maximum volume: 60 Liters
    maximum flow rate: 1.0 L/min
    current analytical method: High Performance Liquid Chromatography; HPLC/UV
    method reference: 2 (OSHA In-house File)
    method classification: Partially Validated

Conditions: HPLC/UV; Acetonitrile extraction; C18 column; 25% methanol 75% water; 1 mL/min; UV Det: 210; Retention time, 4.7 min; DL 8.8 ng/inj; C/P

Wipe Sampling Method:

  • sampling media: Glass Fiber Filter

Bulk Method:

  • Limit the amount of bulk submitted to one gram or one mL.

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