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Chemical Sampling Information (CSI)
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General Description

Synonyms: 1,2,3,4,10,10-Hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro-1,4-endo-endo-5,8-dimethanonaphthalene; Mendrin; Nendrin; Hexadrin

OSHA IMIS Code Number: 1017

Chemical Abstracts Service (CAS) Registry Number: 72-20-8

NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: IO1575000; 31598

Department of Transportation Regulation Number (49 CFR 172.101) and Guide: NA2761 151 Poison

Chemical Description and Physical Properties:

colorless to tan solid with a mild chemical odor
molecular weight: 381
vapor pressure: 2 x 10-7 mm at 25°C
boiling point: decomposes at 245°C

Incompatibilities: Strong oxidizers and acids

Exposure Limits

OSHA Permissible Exposure Limit (PEL):

General Industry: 0.1 mg/m3 (Skin)

Construction Industry: 0.1 mg/m3 TWA (Skin)

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 0.1 mg/m3 TWA (Skin); Appendix A4 (Not Classifiable as a Human Carcinogen)

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 0.1 mg/m3 TWA (Skin)

Health Factors

Carcinogenic Classification:

International Agency for Research on Cancer (IARC): Group 3, not classifiable as to its carcinogenicity to humans

Potential Symptoms: Epileptiform convulsions; stupor, headaches, dizziness; abdominal discomfort, nausea, vomiting; insomnia; aggressive confusion, lethargy, weakness; anorexia; In animals: liver damage

Health Effects: Acute CNS Toxicity (HE4); Suspect teratogen (HE5) LD50 (oral,rat) 7-15 mg/kg

Affected Organs: CNS, liver

Monitoring Methods used by OSHA

Primary Laboratory Sampling/Analytical Method (SLC1):

  • sampling media: Mixed Cellulose Ester Filter (MCEF) 0.8 microns in series with Chromosorb 102 Tube (200/100 mg sections, 20/40 mesh)
    analytical solvent: Toluene
    maximum volume: 120 Liters
    maximum flow rate: 1.0 L/min
    current analytical method: Gas Chromatography; GC/ECD
    method reference: 1 (NIOSH S-284)
    sampling and analytical error: 0.12
    method classification: Fully Validated

Bulk Method:

  • Limit the amount of bulk submitted to one gram or one mL.

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