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Chemical Sampling Information (CSI)
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General Description

Synonyms: 4,6-Dinitro-2-methylphenol; 4,6-Dinitro-o-cresol

OSHA IMIS Code Number: 0975

Chemical Abstracts Service (CAS) Registry Number: 534-52-1

NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: GO9625000; 27370

Department of Transportation Regulation Number (49 CFR 172.101) and Guide: UN1598 Poison

NIOSH Pocket Guide to Chemical Hazards, Dinitro-o-cresol: Physical description, chemical properties, potentially hazardous incompatibilities, and more

Chemical Description and Physical Properties:

yellow solid
molecular weight: 198
vapor pressure: 0.00005 mm
melting point: 187°F

Incompatabilities: Strong oxidizers

Exposure Limits

OSHA Permissible Exposure Limit (PEL):

General Industry: 0.2 mg/m3 (Skin)

Construction Industry: 0.2 mg/m3 TWA (Skin)

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 0.2 mg/m3 TWA (Skin)

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 0.2 mg/m3 TWA(skin)

Health Factors

Potential Symptoms: Sense of well being; headaches; fever; lassitude; profuse sweating, excessive thirst; tachycardia; hyperpnea, coughing, shortness of breath; coma

Health Effects: Cumulative systemic (metabolic) toxin (HE3); Mutagen (HE2)

Affected Organs: CVS, endocrine system, eyes

Monitoring Methods used by OSHA

Primary Laboratory Sampling/Analytical Method (SLC1):

  • sampling media: Mixed Cellulose Ester Filter (MCEF) 0.8 microns in series with Midget Impinger containing 10 mL Ethylene Glycol.
    maximum volume: 180 Liters
    maximum flow rate: 1.5 L/min
    current analytical method: High Performance Liquid Chromatography; HPLC/UL61.
    method reference: 1 (NIOSH S166)
    sampling and analytical error: 0.12
    method classification: Fully Validated
    note: Immediately after sampling remove filter from cassette and add to Ethylene Glycol sample.

Conditions: Column: C18 Mobile Phase: 65:35:0.175 Methanol:Water:Acetic Acid Detector Wavelength: 254nm Detection Limit

Bulk Method:

  • Limit the amount of bulk submitted to one gram or one mL.

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