Powered by GoogleTranslate


General Description

  • Synonyms: DMP; Dimethyl 1,2-benzenedicarboxylate; Dimethyl ester of 1,2-benzenedicarboxylic acid; Dimethyl phthalate; Phthalic acid, dimethyl ester
  • OSHA IMIS Code Number: 0950
  • Chemical Abstracts Service (CAS) Registry Number: 131-11-3
  • NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: TI1575000
  • NIOSH Pocket Guide to Chemical Hazards, Dimethylphthalate: chemical description, physical properties, potentially hazardous incompatibilities, and more

Exposure Limits

  • OSHA Permissible Exposure Limit (PEL):
  • American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV) (2005): 5 mg/m3 TWA
  • National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 5 mg/m3 TWA

Health Factors

  • Carcinogenic Classification:
  • NIOSH Immediately Dangerous To Life or Health Concentration (IDLH): 2,000 mg/m3
  • Potential Symptoms: Irritation of eyes, upper respiratory system; stomach pain; dizziness, disorientation, loss of coordination; INGES. ACUTE: Vomiting, diarrhea, unconsciousness
  • Health Effects: Irritation-Eyes, Nose, Throat---Mild (HE16)
  • Affected Organs: Eyes, respiratory system, GI tract
  • Notes:
    1. A rat 24-hour urine collection following the administration of 0.1 ml of dimethyl phthalate by oral gavage contained 8.1% parent compound; 77.5% of the total excreted phthalate was monomethyl phthalate, and 14.4% was phthalic acid.
    2. A NOAEL for maternal toxicity of 1% was reported for pregnant rats administered 0.25, 1 or 5% dimethyl phthalate in the diet during gestational days 6-15, and no effect of dimethyl phthalate feeding was observed on any parameter of embryo/fetal development.
    3. The steady state absorption rate of dimethyl phthalate (3.95 ± 0.64 µg/cm2/hr) through human skin was reported to be less than 10% the rate through rat skin in vitro.
  • Literature Basis:
    • NIOSH Pocket Guide to Chemical Hazards: Dimethylphthalate.
    • International Chemical Safety Cards (WHO/IPCS/ILO): Dimethyl phthalate.
    • EPA Air Toxics Website: Dimethyl Phthalate. U.S. Environmental Protection Agency Technology Transfer Network.
    • Albro, P.W. and Moore, B.: Identification of the metabolites of simple phthalate diesters in rat urine. J. Chromatogr. 94(0): 209-218, 1974.
    • Field, E.A., et al.: Developmental toxicity evaluation of diethyl and dimethyl phthalate in rats. Teratology 48(1): 33-44, 1993.
    • Pohanish, R.P. (editor): Dimethyl Phthalate. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 936-939.
    • Scott, R.C., Dugard, P.H., Ramsey, J.D. and Rhodes, C.: In vitro absorption of some o-phthalate diesters through human and rat skin. Environ. Health Perspect. 74: 223-227, 1987.
  • Date Last Revised: 05/15/2007

Monitoring Methods used by OSHA

Primary Laboratory Sampling/Analytical Method (SLC1):
  • OSHA Versatile Sampler (OVS-Tenax) - 13 mm Tenax Tube (140/70 mg sections) with a Glass Fiber filter enclosed
  • analytical solvent: Toluene
  • maximum volume: 240 Liters
  • maximum flow rate: 1.0 L/min
  • current analytical method: Gas Chromatography; GC/FID
  • method reference: OSHA Analytical Method (OSHA 104)
  • method classification: Fully Validated

** All Trademarks are the property of their respective owners.

Back to Top

Thank You for Visiting Our Website

You are exiting the Department of Labor's Web server.

The Department of Labor does not endorse, takes no responsibility for, and exercises no control over the linked organization or its views, or contents, nor does it vouch for the accuracy or accessibility of the information contained on the destination server. The Department of Labor also cannot authorize the use of copyrighted materials contained in linked Web sites. Users must request such authorization from the sponsor of the linked Web site. Thank you for visiting our site. Please click the button below to continue.