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Chemical Sampling Information (CSI)
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General Description

OSHA IMIS Code Number: 0660

Chemical Abstracts Service (CAS) Registry Number: 600-25-9

NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: TX5075000; 65332

NIOSH Pocket Guide to Chemical Hazards, 1-Chloro-1-nitropropane: chemical description, physical properties, potentially hazardous incompatibilities, and more

Chemical Description and Physical Properties:
    colorless liquid with an unpleasant odor that causes tears
    molecular weight: 124
    vapor pressure: 5.8 mm at 77°F
    boiling point: 285°F

Exposure Limits

OSHA Permissible Exposure Limit (PEL):
General Industry: 20 ppm, 100 mg/m3

Construction Industry: 20 ppm, 100 mg/m3 TWA
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 2 ppm, 10 mg/m3 TWA

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 2 ppm TWA


Health Factors

Potential Symptoms: In animals: eye irritation; pulmonary edema; liver, kidney, heart damage

Health Effects: Irritation-Eye, Nose, Throat, Skin---Moderate (HE15) Acute lung edema (HE11)

Affected Organs: In animals: respiratory system, liver, kidneys, CVS

Additional Information:

  • Occupational Health Guidelines for Chemical Hazards. US Department of Health and Human Services (DHHS), National Institute for Occupational Safety and Health (NIOSH) Publication No. 81-123, (1981, January). Provides a table of contents of guidelines for many hazardous chemicals. The files provide technical chemical information, including chemical and physical properties, health effects, exposure limits, and recommendations for medical monitoring, personal protective equipment (PPE), and control procedures.

Date Last Revised: 08/24/1992

Monitoring Methods used by OSHA

Primary Laboratory Sampling/Analytical Method (SLC1):
  • sampling media: Chromosorb 108 (400/200 mg sections,60/80 mesh)
    analytical solvent: Ethyl Acetate
    maximum volume: 12 Liters   
    maximum flow rate: 0.2 L/min
    current analytical method: Gas Chromatography; GC/FID
    method reference: 1 (NIOSH S-211)
    sampling and analytical error: 0.15
    method classification: Fully Validated
    note: Chromosorb 108 resin must be washed with methylene chloride and ethyl acetate before use. OSHA personnel may obtain washed tubes from the Salt Lake Technical Center.
On-Site Sampling Techniques/Methods:
  • device: Detector Tube
    manufacturer: MSA
    part #: 91624
    range: 2-75 ppm, Pyrolyzer required
    class: Mfg
  • device: Instrumentation
    manufacturer: Infrared Spectrophotometer
    part #: MIRAN 1A & 1B
    range: 1.6 ppm @ 12.4 um
    class: Mfg
  • device: Instrumentation
    manufacturer: Infrared Spectrophotometer
    part #: MIRAN 103
    range: 0-100 ppm @ 12.4 um
    class: Mfg

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