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General Description

  • OSHA IMIS Code Number: 0660
  • Chemical Abstracts Service (CAS) Registry Number: 600-25-9
  • NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: TX5075000; 65332
  • NIOSH Pocket Guide to Chemical Hazards, 1-Chloro-1-nitropropane: chemical description, physical properties, potentially hazardous incompatibilities, and more
  • Chemical Description and Physical Properties:
    • colorless liquid with an unpleasant odor that causes tears
    • molecular weight: 124
    • vapor pressure: 5.8 mm at 77°F
    • boiling point: 285°F

Exposure Limits

  • OSHA Permissible Exposure Limit (PEL):
    • General Industry: 20 ppm, 100 mg/m3
    • Construction Industry: 20 ppm, 100 mg/m3 TWA
  • American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 2 ppm, 10 mg/m3 TWA
  • National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 2 ppm TWA

Health Factors

  • Potential Symptoms: In animals: eye irritation; pulmonary edema; liver, kidney, heart damage
  • Health Effects: Irritation-Eye, Nose, Throat, Skin---Moderate (HE15) Acute lung edema (HE11)
  • Affected Organs: In animals: respiratory system, liver, kidneys, CVS
  • Additional Information:
    • Occupational Health Guidelines for Chemical Hazards. U.S. Department of Health and Human Services (DHHS), National Institute for Occupational Safety and Health (NIOSH) Publication No. 81-123, (1981, January). Provides a table of contents of guidelines for many hazardous chemicals. The files provide technical chemical information, including chemical and physical properties, health effects, exposure limits, and recommendations for medical monitoring, personal protective equipment (PPE), and control procedures.
  • Date Last Revised: 08/24/1992

Monitoring Methods used by OSHA

Primary Laboratory Sampling/Analytical Method (SLC1):
  • Chromosorb 108 (400/200 mg sections, 60/80 mesh)
  • analytical solvent: Ethyl Acetate
  • maximum volume: 12 Liters   
  • maximum flow rate: 0.2 L/min
  • current analytical method: Gas Chromatography; GC/FID
  • method reference: 1 (NIOSH S-211)
  • sampling and analytical error: 0.15
  • method classification: Fully Validated
  • note: Chromosorb 108 resin must be washed with methylene chloride and ethyl acetate before use. OSHA personnel may obtain washed tubes from the Salt Lake Technical Center (SLTC).
On-Site Sampling Techniques/Methods:
  • Detector Tube
  • manufacturer: MSA
  • part #: 91624
  • range: 2-75 ppm, Pyrolyzer required
  • class: Mfg
  • Instrumentation
  • manufacturer: Infrared Spectrophotometer
  • part #: MIRAN 1A & 1B
  • range: 1.6 ppm @ 12.4 µm
  • class: Mfg
  • Instrumentation
  • manufacturer: Infrared Spectrophotometer
  • part #: MIRAN 103
  • range: 0-100 ppm @ 12.4 µm
  • class: Mfg

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