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General Description

  • Synonyms: Sodium p-Toluenesulfochloramine; para-Toluene Chlorosulfonamide Acid; Chloramine T Trihydrate; n-Sodium, n-chloro, -para-toluene Sulfonamide; Sodium p-Toluenesulfonchloramide Trihydrate
  • OSHA IMIS Code Number: C327
  • Chemical Abstracts Service (CAS) Registry Number: 127-65-1
  • NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: XT5616800
  • Chemical Description and Physical Properties:
    • white or slightly yellow crystals or powder, slight chlorine odor. Soluble in water, insoluble in benzene, chloroform and ether. Decomposes slowly in air, liberating chlorine. Decomposes violently at 130°C
    • molecular weight: 228.66
    • molecular formula: C7 H8 Cl N O2 SNa

Health Factors

  • Potential Symptoms: Eye irritation, pain, conjunctivitis; burning sensation, coughing, wheezing, laryngitis, sore throat; rhinitis; dyspnea (shortness of breath), bronchitis, pneumonitis, possible pulmonary edema; allergic asthma; skin redness, itching, pain; nausea, vomiting, diarrhea.
  • Health Effects: Respiratory sensitization---asthma (HE9); Skin irritation: allergic urticaria; Ingestion Acute: gastrointestinal irritation.
  • Affected Organs: Eyes, respiratory system, skin
  • Notes:
    1. Approved in Europe as an antiseptic for many medical, dental, and veterinary uses, although major market in U.S. is use in whirlpool baths.
    2. FDA approval of chloramine-T for use in aquaculture (fish farming) in the U.S. is being sought (INAD #8086).
  • Literature Basis:
  • Date Last Revised: 06/13/2003

Monitoring Methods used by OSHA

Primary Laboratory Sampling/Analytical Method (SLC1):
  • Polyvinylchloride (PVC) Filter (37mm)
  • maximum volume: 100 Liters
  • maximum flow rate: 1 L/min
  • current analytical method: High Performance Liquid Chromatograph; HPLC/UV
  • analytical solvent: Deionized Water
  • method reference: 2 (OSHA In-House File)
  • method classification: Not Validated
  • note: Protect samples from light.

Column: CN; Mobile Phase: 70:30:0.2 H2O: Acetonitrile: H3PO4; Detector: UV-254nm

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