Captafol
General Description
- Synonyms: cis-N-((1,1,2,2-Tetrachloroethyl)thio)-4-cyclo-hexene- 1.2-Dicarboximide; Folcid; Difolatan
- OSHA IMIS Code Number: 0528
- Chemical Abstracts Service (CAS) Registry Number: 2425-06-1
- NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: GW4900000; 28722
- Chemical Description and Physical Properties:
- solid
- molecular weight: 349
- melting point: 159°-161°C
Exposure Limits
- American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 0.1 mg/m3 TWA (Skin); Appendix A4 (Not Classifiable as a Human Carcinogen)
- National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 0.1 mg/m3 TWA (Skin) Potential Carcinogen
Health Factors
- Health Effects: Dermatitis (HE3); Suspect Teratogen (HE5) Respiratory sensitization (asthma) (HE9) Mutagen (HE2); LD50 (oral, rat) 6200 mg/kg
Primary Laboratory Sampling/Analytical Method (SLC1):
- OSHA Versatile Sampler (OVS-2) - 13 mm tube (270/140 mg sections, 20/60 mesh) with Glass Fiber Filter enclosed
- maximum volume: 240 Liters
- maximum flow rate: 1.0 L/min
- current analytical method: Gas Chromatography; GC/ECD
- method reference: 2 (OSHA in-house file)
- method classification: not validated
Wipe Sampling Method:
- Whatman 41 Filter Paper
Bulk Method:
- Limit the amount of bulk submitted to one gram or one mL.
Conditions:
Column Capillary DB-5 (10 m x 0.32 mm i.d.) with 1 um film Oven temp 220°C; Ret time 4.2 min; Extraction with methanol gave 84% recovery, GC/ECD
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