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Caprolactam (Dust)

General Description

  • Synonyms: Aminocaproic lactam; epsilon-Caprolactam; Hexahydro-2H-azepin-2-one; 2-Oxohexamethyleneimine
  • OSHA IMIS Code Number: 0523
  • Chemical Abstracts Service (CAS) Registry Number: 105-60-2
  • NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: CM3675000
  • NIOSH Pocket Guide to Chemical Hazards, Caprolactam: chemical description, physical properties, potentially hazardous incompatibilities, and more

Exposure Limits

  • American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV) (1997): 5 mg/m3 (inhalable fraction and vapor) TWA; A5
  • National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 1 mg/m3 TWA, 3 mg/m3 STEL

Health Factors

  • Carcinogenic Classification:
  • Potential Symptoms: Acute (short-term) exposure may result in irritation and burning of the eyes, nose, throat, and skin. Headaches, malaise, confusion, and nervous irritation after inhalation. Chronic (long-term) exposure may cause peeling of the hands and some eye, nose, and throat irritation.
  • Health Effects: Irritation-Eye, Nose, Throat, Skin---Moderate (HE15) CNS Effects (HE7)
  • Affected Organs: Eyes, nose, throat, skin, CNS
  • Literature Basis:

Monitoring Methods used by OSHA

Primary Laboratory Sampling/Analytical Method (SLC1):
  • OSHA Versatile Sampler (OVS-7) - 13 mm XAD-7 tube (270/140 mg sections, 20/60 mesh) with Glass Fiber Filter enclosed
  • maximum volume: 100 Liters
  • maximum flow rate: 1.0 L/min (TWA)
  • current analytical method: High Performance Liquid Chromatography; HPLC/UV
  • method reference: OSHA Analytical Method (OSHA PV2012)
  • method classification: Partially Validated

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