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General Description

  • Synonyms: 1-Methyl-4-tert-butylbenzene
  • OSHA IMIS Code Number: 0485
  • Chemical Abstracts Service (CAS) Registry Number: 98-51-1
  • NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: XS8400000
  • Department of Transportation Regulation Number (49 CFR 172.101) and Emergency Response Guidebook: UN2667 Keep Away From Food
  • NIOSH Pocket Guide to Chemical Hazards, p-tert-Butyltoluene: chemical description, physical properties, potentially hazardous incompatibilities, and more
  • Chemical Description and Physical Properties:
    • colorless liquid with an aromatic odor, somewhat like gasoline
    • molecular weight: 148
    • vapor pressure: <1 mm
    • boiling point: 380°F
    • melting point: -62°F
  • Incompatibilities: Oxidizers

Exposure Limits

  • OSHA Permissible Exposure Limit (PEL):
    • General Industry: 10 ppm, 60 mg/m3
    • Construction Industry: 10 ppm, 60 mg/m3 TWA
  • American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 1 ppm, 6.1 mg/m3 TWA
  • National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 10 ppm TWA, 20 ppm STEL

Health Factors

  • Potential Symptoms: Eye, skin irritation; dry nose, throat; headaches; low blood pressure, tachycardia; abnormal cardiovascular system; central nervous system depression; hematopoietic depression
  • Health Effects: CNS Damage (HE7); Nausea (HE4) Cumulative liver, kidney, cardiovascular damage (HE3)
  • Affected Organs: Cardiovascular system, central nervous system, skin, bone marrow, eyes, upper respiratory system

Monitoring Methods used by OSHA

Primary Laboratory Sampling/Analytical Method (SLC1):
  • Charcoal Tube (100/50 mg sections, 20/40 mesh)
  • maximum volume: 24 Liters
  • maximum flow rate: 0.2 L/min (TWA)
  • maximum volume: 3 Liters
  • maximum flow rate: 0.2 L/min (STEL)
  • current analytical method: Gas Chromatography; GC/FID
  • analytical solvent: Carbon Disulfide
  • method reference: 1 (NIOSH 1501 (PDF))
  • sampling and analytical error: 0.11
  • method classification: Partially Validated
Secondary Laboratory Sampling/Analytical Method (SAM2):
  • Instrumentation
  • company: Infrared Spectrophotometer
  • part #: MIRAN 1A & 1B
  • range: 2.0 ppm @ 12.3 µm
  • classification: Mfg
  • Instrumentation
  • company: Infrared Spectrophotometer
  • part #: MIRAN 103
  • range: 0-100 ppm @ 12.3 µm
  • classification: Mfg

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