Powered by GoogleTranslate

Butyl Carbitol

General Description

Synonyms: 2-(2-Butoxyethoxy)ethanol; Butoxydiethylene glycol; Butoxydiglycol; Diethylene glycol monobutyl ether; Diethylene glycol n-butyl ether; Dowanol DB

OSHA IMIS code: 0471

CAS number: 112-34-5

Chemical description and physical properties:

  • colorless liquid
  • molecular formula: C8H18O3
  • molecular weight: 162.2
  • boiling point: 230.4°C
  • flash point: 78°C

Exposure Limits and Health Effects (Updated September 6, 2012)

Standard Set By Exposure Limit Health Effect Codes -- Health Effects and Target Organs
OSHA PEL Not established
NIOSH REL Not established
ACGIH TLV® (2012) 10 ppm (67.5 mg/m3) (inhalable fraction and vapor) TWA  
CAL/OSHA PELs Not established

Carcinogenic classification:

  • NTP: Not listed
  • IARC: Not listed
  • EPA: Not listed

EPA Inhalation Reference Concentration (RfC): Not established

ATSDR Inhalation Minimal Risk Levels (MRLs): Not established

NIOSH IDLH concentration: Not established

Notes on other potential health effects and hazards:

  1. Butyl carbitol is combustible and can form explosive vapor/air mixtures at temperatures above 78°C (NIOSH/IPCS 2004).
  2. Butyl carbitol is moderately irritating and injurious to the eyes but not appreciably irritating to the skin (Bingham et al. 2001).
  3. Butyl carbitol may produce skin lesions and can be absorbed through the skin (Korinth et al. 2003).
  4. Measurement of the metabolite 2-(2-butoxyethoxy)acetic acid in human urine has been used for biomonitoring the exposure of floor lacquerers to butyl carbitol. An 8-hr exposure to 0.05 ±0.03 ppm butyl carbitol resulted in a urinary metabolite concentration of 9.2 ±7.4 mmol/mol creatinine (Laitinen and Pulkkinen 2005).
  5. Rare cases of allergic contact dermatitis have been reported for individuals exposed to butyl carbinol in printing inks, water-based paints, and disinfectants (Berlin et al. 1995; Dawson et al. 1989; Shliemann-Willers et al. 2000).

Partial reference list:

  • Berlin, K., Johanson, G. and Lindberg, M.: Hypersensitivity to 2-(2-butoxyethoxy)ethanol. Contact Dermatitis 32(1): 54, 1995.
  • Bingham, E., Cohrssen, B., and Powell, C.H.: Patty's Toxicology Volumes 1-9 5th ed. John Wiley & Sons. New York, NY, p. V7 203, 2001.
  • Dawson, T.A.J., Black, R.J., Strang, W.C., Millership, J.S., and Davies, I.A.I.: Delayed and immediate hypersensitivity to carbitols. Contact Dermatitis 21(1): 52-53, 1989.
  • NIOSH/CEC/IPCS: International Chemical Safety CardDiethylene Glycol Monobutyl Ether. April 19, 2004.
  • Korinth, G., Goen, T., Lakemeyer, M., Broding, H.C., and Drexler, H.: Skin strain and its influence on systemic exposure to a glycol ether in offset printing workers. Contact Dermatitis 49(5):248-54, November 2003.
  • Laitinen, J. and Pulkkinen, J.: Biomonitoring of 2-(2-alkoxyethoxy)ethanols by analysing urinary 2-(2-alkoxyethoxy)acetic acids. Toxicol. Lett. 156(1): 117-126, 2005.
  • OSHA: Sampling and Analytical MethodsButyl Carbitol. February 1993.
  • Schliemann-Willers, S., Bauer, A., and Elsner, P.: Occupational contact dermatitis from diethylene glycol monobutyl ether in a podiatrist. Contact Dermatitis 43(4): 225, 2000.

Chemical Sampling Information

By Name


By CAS Number

** All Trademarks are the property of their respective owners.

Back to Top

Thank You for Visiting Our Website

You are exiting the Department of Labor's Web server.

The Department of Labor does not endorse, takes no responsibility for, and exercises no control over the linked organization or its views, or contents, nor does it vouch for the accuracy or accessibility of the information contained on the destination server. The Department of Labor also cannot authorize the use of copyrighted materials contained in linked Web sites. Users must request such authorization from the sponsor of the linked Web site. Thank you for visiting our site. Please click the button below to continue.