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sec-Butyl Alcohol

General Description

  • Synonyms: 2-Butanol; sec-Butanol; Methyl ethyl carbinol; Butylene hydrate; 2-Hydroxybutane
  • OSHA IMIS Code Number: 0461
  • Chemical Abstracts Service (CAS) Registry Number: 78-92-2
  • NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: EO1750000
  • Department of Transportation Regulation Number (49 CFR 172.101) and Emergency Response Guidebook: 1120 129
  • NIOSH Pocket Guide to Chemical Hazards, sec-Butyl alcohol: chemical description, physical properties, potentially hazardous incompatibilities, and more

Exposure Limits

  • OSHA Permissible Exposure Limit (PEL):
  • American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 100 ppm, 303 mg/m3 TWA - listed under sec-Butanol
  • National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 100 ppm, 305 mg/m3 TWA; 150 ppm, 455 mg/m3 STEL

Health Factors

  • NIOSH Immediately Dangerous To Life or Health Concentration (IDLH): 2,000 ppm
  • Potential Symptoms: Eye irritation (redness, pain, blurred vision); dry skin, dermatitis; headache; dizziness, drowsiness, narcosis.
  • Health Effects: Irritation-Eye, Nose, Throat, Skin---Mild (HE16); Narcosis (HE8); Explosive, Flammable, Safety (HE18)
  • Affected Organs: Eyes, skin, respiratory system, CNS
  • Notes:
    1. Above 24°C, explosive vapor/air mixtures may be formed.
    2. Listed among FDA's "food additives permitted for direct addition to food for human consumption" (21CFR 172.515)
  • Literature Basis:
  • Date Last Revised: 01/21/2004

Monitoring Methods used by OSHA

Primary Laboratory Sampling/Analytical Method (SLC1):
  • Charcoal Tube (100/50 mg sections, 20/40 mesh)
  • maximum volume: 10 Liters
  • maximum flow rate: 0.2 L/min
  • current analytical method: Gas Chromatography; GC/FID
  • analytical solvent: (99:1) Carbon Disulfide/Isopropanol
  • alternative solvent: (99:1) Carbon Disulfide/Dimethylformamide
  • method reference: NIOSH Manual of Analytical Methods (NIOSH 1401 (PDF))
  • method classification: Fully Validated
On-Site Sampling Techniques/Methods:
  • Detector Tube
  • manufacturer: AUER/MSA
  • model/type: Ethanol-100, MSA P/N 804136, AUER P/N 5086-818
  • sampling information: follow manufacturer's instructions
  • upper measurement limit: 5100 ppm
  • detection limit: approximately 150 ppm
  • overall uncertainty: unknown
  • method reference: on-site air secondary (manufacturer)
  • Detector Tube
  • manufacturer: Gastec
  • model/type: 115
  • sampling information: 3 strokes
  • upper measurement limit: 150 ppm
  • detection limit: 1 ppm
  • overall uncertainty: 25% for 5 to 50 ppm, 16% for 50 to 150 ppm
  • method reference: on-site air secondary (manufacturer)
  • Detector Tube
  • manufacturer: Matheson-Kitagawa
  • model/type: 8014-189U
  • sampling information: 2 or 4 strokes
  • upper measurement limit: 300 ppm
  • detection limit: approximately 4 ppm
  • overall uncertainty: unknown
  • method reference: on-site air secondary (manufacturer)

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