Synonyms: p-Aminodiphenyl; 4-Aminobiphenyl
OSHA IMIS Code Number: 0162
Chemical Abstracts Service (CAS) Registry Number: 92-67-1
NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: DU8925000; 20613
Chemical Description and Physical Properties:
colorless crystals which turn purple on contact with air; floral odor
molecular weight: 169
boiling point: 575°F
melting point: 127°F
OSHA Permissable Exposure Limit (PEL):
American Conference of Governmental Industrial Hygenists (ACGIH) Threshold Limit Value (TLV): Appendix A1 (Confirmed Human Carcinogen)
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 29 CFR 1910.1011 Potential Carcinogen
National Toxicology Programs (NTP): Known to be a Human Carcinogen [79 KB PDF, 2 pages]
International Agency for Research on Cancer (IARC): Group 1, carcinogenic to humans [1 MB PDF, 454 pages]
Potential Symptoms: Headaches, lethargy, dizziness; dyspnea; ataxia, weakness; methemoglobinemia; urinary burning; acute hemorrhage cystitis, (carcinogenic)
Health Effects: Cancer---Currently regulated by OSHA as carcinogen; chiefly work practice standards (HE1) LD50 (oral, rat) 500 mg/kg
Skin Absorption: Yes
Affected Organs: bladder, skin
Primary Laboratory Sampling/Analytical Method (SLC1):
sampling media: Coated Glass Fiber Filters (37 mm) in 3 piece cassette. Coating is Sulfuric Acid.
maximum volume: 100 Liters
maximum flow rate: 0.1 L/min
current analytical method: Gas Chromatography; GC/ECD
method reference: 2 (OSHA 93)
sampling and analytical error: 0.09
method classification: Fully Validated
note: Within ten hours after sampling, transfer filter to glass vial containing 2 mL deionized water. Filters may be obtained by OSHA personnel from the Salt Lake Technical Center.
Conditions: column: C18 mobile phase: 65% methanol 35% water ultra violet detector: 280nm, 220nm fluoresence detector: excitation: 265nm emissions: 389nm retention time: 8.9 min detection limit: 0.06 ug/sample
Wipe Sampling Method:
sampling media: Glass Fiber Filter
** All Trademarks are the property of their respective owners.
- Limit the amount of bulk submitted to one gram or one mL.
Accessibility Assistance: Contact the OSHA Directorate of Technical Support and Emergency Management at (202) 693-2300 for assistance accessing PDF materials.