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Aldrin

General Description

  • Synonyms: 1,2,3,4,10,10-Hexachloro-1,4,4a,5,8,8a-hexahydro-exo-1,4-endo-5,8-dimethanonaphthalene; Octalene; Aldrite; Aldrosol; HHDN; Seedrin; NCI-C00044
  • OSHA IMIS Code Number: 0125
  • Chemical Abstracts Service (CAS) Registry Number: 309-00-2
  • NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: IO2100000
  • Department of Transportation Regulation Number (49 CFR 172.101) and Emergency Response Guidebook: 2761 151
  • NIOSH Pocket Guide to Chemical Hazards, Aldrin: chemical description, physical properties, potentially hazardous incompatibilities, and more

Exposure Limits

  • OSHA Permissible Exposure Limit (PEL):
  • American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 0.25 mg/m3 TWA; Skin; Appendix A3 (Confirmed Animal Carcinogen with Unknown Relevance to Humans)
  • National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 0.25 mg/m3 TWA; Skin; Appendix A - Potential Occupational Carcinogen

Health Factors

  • Carcinogenic Classification:
  • NIOSH Immediately Dangerous To Life or Health Concentration (IDLH): 25 mg/m3>
  • Potential Symptoms: Headache, dizziness; nausea, vomiting, malaise; mild erythema of skin; impairment of memory, emotional disturbances; tremors, hyperexcitability, myoclonic jerks of limbs; clonic-tonic convulsions, coma, respiratory failure (carcinogenic)
  • Health Effects: CNS Disturbances (HE7); LD50 (oral, rat) 39-45 mg/kg; (dermal, rat) 98 mg/kg
  • Affected Organs: CNS, liver, kidneys
  • Note: Metabolized in the body to dieldrin, also a previously used insecticide. Neither has been produced or used since 1989, but may remain in buildings treated for termites or in chemical dumping sites.
  • Literature Basis:
    • (impairment of memory, emotional disturbances, tremors, hyperexcitability, and seizures) Sullivan, J.B., Jr., and Van Ert, M.: Organochlorine pesticides (Chapter 102). Materials Toxicology, Clinical Principles of Environmental Health, Sullivan, J.B. Jr., and Krieger, G.R. eds. Baltimore: Williams & Wilkins, pp. 1042-1047, 1992.
    • (headache, dizziness, nausea, vomiting; skin erythema) Bus, J.S. and Leber, A.P.: Miscellaneous chlorinated hydrocarbon pesticides (Chapter 69), in Patty's Toxicology, 5th Ed., Vol. 5, E. Bingham, B. Cohrssen and C.H. Powell, eds. New York: John Wiley & Sons, Inc., pp. 635-640, 2001.
    • (acute toxicity data - LD50s)
  • Date Last Revised: 01/08/2002

Monitoring Methods used by OSHA

Primary Laboratory Sampling/Analytical Method (SLC1):
  • Glass Fiber Filter (37 mm) in series with Midget Fritted Glass Bubbler (MFGB) containing 15mL Ethylene Glycol
  • maximum volume: 240 Liters
  • maximum flow rate: 1.0 L/min
  • current analytical method: Gas Chromatography; GC/ECD
  • method reference: OSHA modified NIOSH Manual of Analytical Methods (OSHA modified NIOSH 5502 (PDF))
  • method classification: Partially Validated
Wipe Sampling Method:
  • Glass Fiber Filter
  • analytical solvent: Dry

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