 |
Chemical Sampling Information: |
|
| Vinyl Acetate |
|
General Description
Synonyms: Acetic acid, vinyl ester; Acetic acid, ethenyl ester; 1-Acetoxyethylene; Ethenyl acetate; Ethenyl ethanoate; VAC; Vinyl acetate monomer; Vinyl ethanoate
Ethenyl acetate
OSHA IMIS Code Number: 2572
Chemical Abstracts Service (CAS) Registry Number: 108-05-4
NIOSH, Registry of Toxic Effects (RTECS) Identification Number: AK0875000
Department of Transportation Regulation Number (49 CFR 172.101) and Guide: 1301 129P
NIOSH Pocket Guide to Chemical Hazards, Vinyl Acetate: chemical description, physical properties, potentially hazardous incompatibilities, and more
Exposure Limits
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 10 ppm, 35 mg/m3 TWA; 15 ppm, 53 mg/m3 STEL; Appendix A3 - Confirmed Animal Carcinogen with Unknown Relevance to Humans
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 4 ppm, 15 mg/m3 Ceiling (15 Minutes)
Health Factors
International Agency for Research on Cancer (IARC) carcinogenic classification: Group 2B, Possibly carcinogenic to humans.
Potential symptoms: Eye, nose, throat irritation; hoarseness, cough, shortness of breath; loss of smell; eye redness, pain, minor burns; skin redness, blisters; INGES ACUTE: Drowsiness; headache.
Health Effects: Irritation-Eye, Nose, Throat, Skin---Mild (HE16); Explosive, Flammable (HE18).
Affected organs: Respiratory system, eyes, skin
Note: OSHA does not have a PEL for vinyl acetate. A workplace standard of 10 ppm has been proposed by a manufacturer, based upon human-equivalent modeling of rat experiments involving the intracellular production of the metabolites, acetic acid and acetaldehyde.
Date Last Revised: 07/29/2003
Literature Basis:
- International Chemical Safety Cards (WHO/IPCS/ILO): Vinyl Acetate (monomer).
- Bogdanffy, M.S., Sarangapani, R., Plowchalk, D.R., Jarabek, A. and Andersen, M.E.: A biologically based risk assessment for vinyl acetate-induced cancer and noncancer inhalation toxicity. Toxicol. Sci. 51(1): 19-35, 1999.
Monitoring Methods used by OSHA
Laboratory Sampling/Analytical Method:
-
sampling media: Ambersorb XE-347 Tube (Orbo-92) (160/80 mg sections)
analytical solvent: (95:5) Methylene Chloride:Methanol (v/v)
maximum volume: 24 Liters maximum flow rate: 0.1 L/min (TWA)
maximum volume: 3 Liters maximum flow rate: 0.2 L/min (STEL)
current analytical method: Gas Chromatography; GC/FID
method reference: OSHA Manual of Analytical Methods (OSHA 51)
method classification: Fully Validated
-
sampling media: Ambersorb XE-347 Tube (Orbo-92) (160/80 mg sections)
analytical solvent: (99:1) Carbon Disulfide:Dimethylformamide (v/v)
maximum volume: 24 Liters maximum flow rate: 0.1 L/min (TWA)
maximum volume: 3 Liters maximum flow rate: 0.2 L/min (STEL)
current analytical method: Gas Chromatography; GC/FID
method reference: OSHA SLTC In-House File
method classification: Not Validated
On-Site Sampling Techniques/Methods:
-
device: Detector Tube
manufacturer: Gastec
model/type: 143
sampling information: 1 to 4 strokes
upper measurement limit: 250 ppm
detection limit: 1 ppm
overall uncertainty: 25% for 10 to 20 ppm, 16% for 20 to 100 ppm
method reference: on-site air secondary (manufacturer)
-
device: Detector Tube
manufacturer: Gastec
model/type: 141
sampling information: 1 stroke
upper measurement limit: 0.9%
detection limit: 0.006%
overall uncertainty: 16% for 0.024 to 0.18%, 8% for 0.18 to 0.9%
method reference: on-site air secondary (manufacturer)
-
device: Detector Tube
manufacturer: Matheson-Kitagawa
model/type: 8014-237S
sampling information: follow manufacturer's instructions
upper measurement limit: 120 ppm
detection limit: approximately 5 ppm
overall uncertainty: unknown
method reference: on-site air secondary (manufacturer)
* All Trademarks are the property of their respective owners.
|
|
|
|
 |
|
Back to Top
www.osha.gov
