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Vinyl Acetate Chemical Sampling Information:
Vinyl Acetate

General Description
    Synonyms: Acetic acid, vinyl ester; Acetic acid, ethenyl ester; 1-Acetoxyethylene; Ethenyl acetate; Ethenyl ethanoate; VAC; Vinyl acetate monomer; Vinyl ethanoate Ethenyl acetate

    OSHA IMIS Code Number: 2572

    Chemical Abstracts Service (CAS) Registry Number: 108-05-4

    NIOSH, Registry of Toxic Effects (RTECS) Identification Number: AK0875000

    Department of Transportation Regulation Number (49 CFR 172.101) and Guide: 1301 129P

    NIOSH Pocket Guide to Chemical Hazards, Vinyl Acetate: chemical description, physical properties, potentially hazardous incompatibilities, and more
Exposure Limits
    American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 10 ppm, 35 mg/m3 TWA; 15 ppm, 53 mg/m3 STEL; Appendix A3 - Confirmed Animal Carcinogen with Unknown Relevance to Humans

    National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 4 ppm, 15 mg/m3 Ceiling (15 Minutes)
Health Factors
    International Agency for Research on Cancer (IARC) carcinogenic classification: Group 2B, Possibly carcinogenic to humans.

    Potential symptoms: Eye, nose, throat irritation; hoarseness, cough, shortness of breath; loss of smell; eye redness, pain, minor burns; skin redness, blisters; INGES ACUTE: Drowsiness; headache.

    Health Effects: Irritation-Eye, Nose, Throat, Skin---Mild (HE16); Explosive, Flammable (HE18).

    Affected organs: Respiratory system, eyes, skin

    Note: OSHA does not have a PEL for vinyl acetate. A workplace standard of 10 ppm has been proposed by a manufacturer, based upon human-equivalent modeling of rat experiments involving the intracellular production of the metabolites, acetic acid and acetaldehyde.

    Date Last Revised: 07/29/2003

    Literature Basis:
    • International Chemical Safety Cards (WHO/IPCS/ILO): Vinyl Acetate (monomer).
    • Bogdanffy, M.S., Sarangapani, R., Plowchalk, D.R., Jarabek, A. and Andersen, M.E.: A biologically based risk assessment for vinyl acetate-induced cancer and noncancer inhalation toxicity. Toxicol. Sci. 51(1): 19-35, 1999.
Monitoring Methods used by OSHA
    Laboratory Sampling/Analytical Method:

    • sampling media: Ambersorb XE-347 Tube (Orbo-92) (160/80 mg sections)
      analytical solvent: (95:5) Methylene Chloride:Methanol (v/v)
      maximum volume: 24 Liters   maximum flow rate: 0.1 L/min (TWA)
      maximum volume: 3 Liters   maximum flow rate: 0.2 L/min (STEL)
      current analytical method: Gas Chromatography; GC/FID
      method reference: OSHA Manual of Analytical Methods (OSHA 51)
      method classification: Fully Validated


    • sampling media: Ambersorb XE-347 Tube (Orbo-92) (160/80 mg sections)
      analytical solvent: (99:1) Carbon Disulfide:Dimethylformamide (v/v)
      maximum volume: 24 Liters   maximum flow rate: 0.1 L/min (TWA)
      maximum volume: 3 Liters   maximum flow rate: 0.2 L/min (STEL)
      current analytical method: Gas Chromatography; GC/FID
      method reference: OSHA SLTC In-House File
      method classification: Not Validated

    On-Site Sampling Techniques/Methods:

    • device: Detector Tube
      manufacturer: Gastec
      model/type: 143
      sampling information: 1 to 4 strokes
      upper measurement limit: 250 ppm
      detection limit: 1 ppm
      overall uncertainty: 25% for 10 to 20 ppm, 16% for 20 to 100 ppm
      method reference: on-site air secondary (manufacturer)


    • device: Detector Tube
      manufacturer: Gastec
      model/type: 141
      sampling information: 1 stroke
      upper measurement limit: 0.9%
      detection limit: 0.006%
      overall uncertainty: 16% for 0.024 to 0.18%, 8% for 0.18 to 0.9%
      method reference: on-site air secondary (manufacturer)


    • device: Detector Tube
      manufacturer: Matheson-Kitagawa
      model/type: 8014-237S
      sampling information: follow manufacturer's instructions
      upper measurement limit: 120 ppm
      detection limit: approximately 5 ppm
      overall uncertainty: unknown
      method reference: on-site air secondary (manufacturer)
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  Chemical Sampling Information:
  Vinyl Acetate
  General Description
  Exposure Limits
  Health Factors
  Monitoring
     
     
     
     
     
     
 
 
 
 
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