<< Back to Chemical Sampling Information

Chemical Sampling Information (CSI)
Search (use word(s)/phrase)
Table of Contents
By Name
A B C D E F G H I J K L M
N O P Q R S T U V W X Y Z

By CAS Number
Quick Links
General Description

Synonyms: 3,3'Dimethylbenzidine

OSHA IMIS Code Number: 2450

Chemical Abstracts Service (CAS) Registry Number: 119-93-7

NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: DD1225000; 14667

NIOSH Pocket Guide to Chemical Hazards, o-Tolidine: Chemical description, physical properties, potentially hazardous incompatibilities, and more
Exposure Limits

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): Appendix A3 (Confirmed Animal Carcinogen with Unknown Relevance to Humans)

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 0.02 mg/m3 Ceiling (60 min); Potential carcinogen

Health Factors

Carcinogenic Classification:
International Agency for Research on Cancer (IARC): Group 2B, possibly carcinogenic to humans (3,3'-Dimethylbenzidine and 3,3'-dimethylbenzidine-based dyes) [479 KB PDF, 63 pages]

National Toxicology Program (NTP): Reasonably anticipated to be a human carcinogen (3,3'- Dimethylbenzidine and Dyes Metabolized to 3,3'-Dimethlybenzidine) [183 KB PDF, 3 pages]
Monitoring Methods used by OSHA

Primary Laboratory Sampling/Analytical Method (SLC1):
  • sampling media: Coated Glass Fiber Filters (37 mm) in 3 piece cassette. Coating is Sulfuric Acid.
    maximum volume: 100 Liters   
    maximum flow rate:     1.0 L/min
    current analytical method: Gas Chromatography; GC/ECD
    method reference: 2 (OSHA 71)
    sampling and analytical error: 0.13
    method classification: Fully Validated
    note: Within ten hours after sampling, transfer filter to glass vial containing 2 mL deionized water. Filters may be obtained by OSHA personnel from SLTC.
Conditions: Zorbax C18; 60% methanol 40% water; 1 mL/min; UV Det: 280; DL 0.01 ug/sample; C/P DB

Wipe Sampling Method: Yes, with Glass Fiber Filter

Bulk Method: Limit the amount of bulk submitted to one gram or one mL.

** All Trademarks are the property of their respective owners.
Page last updated: 01/19/1999

Accessibility Assistance: Contact the OSHA Directorate of Technical Support and Emergency Management at (202) 693-2300 for assistance accessing PDF materials.