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Chemical Sampling Information
Rifampicin
 Field Definitions
 Analytical Methods
 Health Guidelines
General Description

NAME: Rifampicin

SYNONYM(s): 5,6,9,17,19,21-hexahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-8-[N-
(4-methyl-1-piperazinyl)formimidoyl]-2,7-[epoxypentadeca(1,11,13)trienimino]-
naphtho(2,1-b)furan-1,11(2H)-dione-21-acetate; 3-(4-methylpiperazinyliminomethyl) rifamycin SV; NSC113926; Rifampin

IMIS: R300

CAS: 13292-46-1

DESCRIPTION: orange to brown powder

MW: 823.0
VP: N/A
MOLFM: C43H58N4O12
BP: N/A
MP: 183-188° C

Exposure Limits
Health Factors



SYMPTOM(s): irritant to skin, eyes, mucous membranes, and respiratory system; may cause nausea, vomiting, excessive tiredness, abnormal liver functioning resulting in yellowing of the eyes

HEALTH EFFECTS: irritant to skin, eyes, mucous membranes, and respiratory system

ORGAN: skin, eyes, respiratory system, mucous membranes

Monitoring

PRIMARY SAMPLING/ANALYTICAL METHOD (SLC1):

MEDIA: 37 mm Glass Fiber Filter
ANL SOLVENT: Acetonitrile
MAX V: 480 liters MAX F: 2 L/min (TWA)
ANL 1: High Performance Liquid Chromatography; HPLC/UV
REF: 2(OSHA In-house file) CLASS: Partially Validated



COND: Column: C18; Mobile Phase: 30:70 acetonitrile:0.025 M (NH4)H2PO4 at 1.5 ml/min; Detector Wavelength: 238nm


Revision Date: 09/11/2002
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