Synonyms: EGPE; Ethylene glycol monopropyl ether; Propyl Cellosolve; Propylglycol
OSHA IMIS Code Number: P136
Chemical Abstracts Service (CAS) Registry Number: 2807-30-9
NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: KM2800000
Chemical Description and Physical Properties:
clear colorless flammable liquid; soluble in water and most solvents; mild reasonably pleasant odor
molecular weight: 104.149
vapor pressure: 130 Pa @ 25°C
molecular formula: C5H12O2
boiling point: 149.5-150.5°C
melting point: -90°C
Potential Symptoms: Eye, nose, throat and skin irritation; cough, sore throat; eye redness, pain; dry skin.
Health Effects: Irritation-Eyes---Marked (HE14); Irritation-Nose, Throat, Skin---Mild (HE16); Blood disorders (HE12)
Affected Organs: Eyes, skin, respiratory system, blood
- Explosive vapor/air mixtures may be formed with 2-propoxyethanol at temperatures above 57°C.
- No reports of adverse effects on humans were found in the literature. Oral and inhalational studies in rats indicated red blood cells as the primary site of action (hematuria), with secondary changes occurring in spleen, liver and kidneys. The overall NOEL of 2-propoxyethanol in inhalational studies was reported to be 200 ppm.
- International Chemical Safety Cards (WHO/IPCS/ILO): Ethylene glycol monopropyl ether.
- Katz, G.V., Krasavage, W.J. and Terhaar, C.J.: Comparative acute and subchronic toxicity of ethylene glycol monopropyl ether and ethylene glycol monopropyl ether acetate. Environ. Health Perspect. 57: 165-175, 1984.
Date Last Revised: 09/20/2006
Primary Laboratory Sampling/Analytical Method (SLC1):
- sampling media: Charcoal Tube (100/50 mg sections, 20/40 mesh)
analytical solvent: (95:5) Methylene Chloride: Methanol
maximum volume: 10 Liters
maximum flow rate: 0.2 L/min
current analytical method: Gas Chromatography; GC/FID
method reference: OSHA (In-House File)
method classification: Not Validated
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