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Chemical Sampling Information
Pindone (2-Pivalyl-1,3-indandione)
 Field Definitions
 Analytical Methods
 Health Guidelines
General Description

NAME: Pindone (2-Pivalyl-1,3-indandione)

SYNONYM(s): 1,3-Dioxo-2-pivaloy-lindane; Pival Pivalyl valone; 2-Pivalyl-1,3-Indandione prior to 9/1/89

IMIS: 2125

CAS: 83-26-1

NIOSH: RTECS NK6300000; 42628

DOT: UN2472 Poison

DESCRIPTION:

0.5% Concentration: inert solid, bright yellow with almost no odor, usually as a dust.
MW: 230
MP: 110 C

INCOM: None hazardous

Exposure Limits

OSHA GENERAL INDUSTRY PEL: 0.1 mg/m3

OSHA CONSTRUCTION INDUSTRY PEL: 0.1 mg/m3 TWA

ACGIH TLV: 0.1 mg/m3 TWA

NIOSH REL: 0.1 mg/m3 TWA

Health Factors

SYMPTOM(s): Epistaxis, excess bleeding from minor cuts, bruises; smokey urine, black tarry stools; abdominal, back pain

HEALTH EFFECTS: Cumulative anticoagulant effect (Warfarin analogy) (HE3)

ORGAN: Blood prothrombin

Monitoring

PRIMARY SAMPLING/ANALYTICAL METHOD (SLC1):



MEDIA: Polytetrafluoroethylene (FA) Filter (1.0 micron) in series with Tenax GC tube (60/30 mg sections)
ANL SOLVENT: Methanol
MAX V: 200 Liters   MAX F: 1.0 L/min
ANL 1: High Performance Liquid Chromatography; HPLC/UV
REF: 2 (OSHA In-House File)
CLASS: Not Validated
NOTE: Immediately after sampling place front section of Tenax GC tube in vial with the Teflon filter. Seal and ship with backup section of Tenax GC tube.

COND: (Unknown whether 1 micron or .5 micron filter was used as the sampling media), Methanol extraction: C18 column; 55% methanol 45% water, PIC A; 1.9 mL/min; UV Det: 280, 229; Retention time, 6.5 min; C/P YC

BULK METHOD:

Limit the amount of bulk submitted to one gram or one mL.


Revision Date: 08/24/1992
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