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3-Phenyltoluene

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General Description
    Synonyms: 3-methylbiphenyl; m-methylbiphenyl; 3-methyl-1,1'-biphenyl; 3-methyldiphenyl

    OSHA IMIS Code Number: P219

    Chemical Abstracts Service (CAS) Registry Number: 643-93-6

    Chemical Description and Physical Properties: Yellow liquid; does not mix with water
      molecular formula: C6H5C6H5CH3
      molecular weight: 168.24
      boiling range: 272°C
      flash point: >110°C
      melting range: -15°C
Health Factors
    Potential symptoms: May cause irritation of eyes, respiratory tract, skin, and digestive tract.

    Health Effects: No human studies were found. Potential Irritation-Eye, Nose, Throat, Bronchi, Lungs---Moderate (HE15)

    Affected organs: Eyes, respiratory system, skin

    Notes:
    1. OSHA does not have a PEL for 3-phenyltoluene, and its toxicological properties (e.g., acute LD50, LC50, toxicokinetics, and chronic effects in animals) have not been fully investigated.
    2. 3-Phenyltoluene should be handled with caution, since the occupational exposure to a compound with similar chemical structure, diphenyl, has been associated with toxicity to the peripheral and central nervous systems, including a significantly increased risk for the development of Parkinson’s disease.

    Date Last Revised: 09/06/2006

    Literature Basis:
    • Acros Organics.: Material Safety Data Sheet: 3-Phenyltoluene, 95%.
    • Wastensson, G., Hagberg, S., Andersson, E, Johnels, B. and Barregård, L.: Parkinson’s disease in diphenyl-exposed workers—a causal association? Parkinsonism Relat. Disord. 12(1): 29-34, 2006.

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