NAME: Methylene bisphenyl isocyanate

SYNONYM(s): 4,4-Diphenylmethane diisocyanate; MDI; 4,4-Diisocyanadiphenyl-methane; Methylene bis(4-phenylisocyanate); Methylene Bis(Phenyl Isocyanate)

IMIS: 1073

CAS: 101-68-8

NIOSH: RTECS NQ9350000; 44210

DOT: UN2489 Keep Away From Food

DESCRIPTION:

White to light-yellow flakes; odorless.
MW: 250
BP: 342 F
VP: 0.05 mm
MP: 99 F

INCOM: Strong alkalies, acids, alcohol

OSHA GENERAL INDUSTRY PEL: 0.02 ppm, 0.2 mg/m3 Ceiling

OSHA CONSTRUCTION INDUSTRY PEL: 0.02 ppm, 0.2 mg/m3 Ceiling

ACGIH TLV: 0.005 ppm, 0.051 mg/m3 TWA

NIOSH REL: 0.005 ppm TWA; 0.020 ppm Ceiling (10 min)

IARC: Group 3, not classifiable as to its carcinogenicity to humans

SYMPTOM(s): Eye, nose, throat irritation; coughing, pulmonary secretions, chest pain, dyspnea, asthma

HEALTH EFFECTS: Asthma (HE9) Irritation-Eye, Nose, Throat, Skin---Marked (HE14)

ORGAN: Respiratory system, eyes

PRIMARY SAMPLING/ANALYTICAL METHOD (SLC1):

MEDIA: Coated Glass Fiber Filter (37 mm open face) Coated with 1.0 mg 1-(2-Pyridyl)piperazine
ANL SOLVENT: 90/10 (v/v) Acetonitrile/Dimethyl Sulfoxide
MIN T: 15 Minutes   MAX F: 1.0 L/min (Ceiling)
ANL 1: High Performance Liquid Chromatography; HPLC/UV/FLU
REF: (OSHA 47)
SAE: 0.17
CLASS: Fully Validated
NOTE: OSHA personnel may obtain coated filter from SLTC and refrigerate until use.

COND: Column: Mobile Phase: Detector Wavelength: Detection Limit:

BULK METHOD:

Limit the amount of bulk submitted to one gram or one mL.