Chemical Sampling Information
	2-Methoxyethyl acetate
Quick Links General Description Exposure Limits Health Factors Monitoring Search    [use word(s)/phrase] Table of Contents By Name A B C D E F G H I J K L M N O P Q R S T U V W X Y Z By CAS Number General Description Synonyms: EGMEA; Ethylene glycol monomethyl ether acetate; Glycol monomethyl ether acetate; 2-Methoxyethanol acetate; Methyl Cellosolve® acetate OSHA IMIS Code Number: 1170 IMIS Name History: Methyl Cellosolve® acetate prior to 7/26/2005 Chemical Abstracts Service (CAS) Registry Number: 110-49-6 NIOSH, Registry of Toxic Effects (RTECS) Identification Number: KL5950000 Department of Transportation Regulation Number (49 CFR 172.101) and Guide: 1189 129 NIOSH Pocket Guide to Chemical Hazards, Methyl Cellosolve® acetate: chemical description, physical properties, potentially hazardous incompatibilities, and more Exposure Limits OSHA Permissible Exposure Limit (PEL) for General Industry: 29 CFR 1910.1000 Z-1 Table -- 25 ppm, 120 mg/m3 TWA; Skin OSHA Permissible Exposure Limit (PEL) for Construction Industry: 29 CFR 1926.55 Appendix A -- 25 ppm, 120 mg/m3 TWA; Skin OSHA Permissible Exposure Limit (PEL) for Maritime: 29 CFR 1915.1000 Table Z-Shipyards -- 25 ppm, 120 mg/m3 TWA; Skin American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 0.1 ppm, 0.5 mg/m3 TWA; Skin National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 0.1 ppm, 0.5 mg/m3 TWA; Skin Health Factors NIOSH Immediately Dangerous To Life or Health Concentration (IDLH): 200 ppm Potential symptoms: Eye, nose, and throat irritation; coughing, shortness of breath, pulmonary edema; kidney, brain damage; dizziness, drowsiness, headache; dry skin; in animals: narcosis; reproductive, teratogenic effects; SKIN ABS; INGES ACUTE: Abdominal pain, nausea, vomiting; weakness; unconsciousness. Health Effects: Irritiation-Eyes, Nose, Throat, Skin---Mild (HE16); Blood disorders (HE12); CNS effects (HE7); Kidney damage (HE3); Suspected reproductive effects (HE5). Affected organs: Eyes, respiratory system, kidneys, brain, CNS, PNS, reproductive system, hematopoietic system. Note: The acetate ester is rapidly converted in the body to methyl cellusolve (2-methoxyethanol), which is further metabolized to aldehyde and acid metabolites that are thought to be involved in reproductive and developmental toxicity, including teratogenicity (see file for Methyl Cellosolve). Date Last Revised: 12/14/2004 Literature Basis: NIOSH Pocket Guide to Chemical Hazards: Methyl Cellosolve® acetate. International Chemical Safety Cards (WHO/IPCS/ILO): 2-Methoxyethyl Acetate. Johanson, G.: Toxicity review of ethylene glycol monomethyl ether and its acetate ester. Crit. Rev. Toxicol. 30(3): 307-345, 2000. Pohanish, R.P. (editor): Methoxyethyl Acetate. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 2. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 1507-1509. Monitoring Methods used by OSHA Laboratory Sampling/Analytical Method: sampling media: Charcoal Tube (100/50 mg sections, 20/40 mesh) analytical solvent: (95:5) Methylene Chloride:Methanol maximum volume: 10 Liters   maximum flow rate: 0.1 L/min current analytical method: Gas Chromatography; GC/FID method reference: OSHA Analytical Method (OSHA 53) method classification: Fully Validated note: Samples for 2-methoxyethyl acetate and/or for 2-ethoxyethyl acetate should be refrigerated upon receipt at the analytical laboratory. sampling media: Charcoal Tube (100/50 mg sections, 20/40 mesh) analytical solvent: (95:5) Methylene Chloride:Methanol maximum volume: 48 Liters   maximum flow rate: 0.1 L/min (long term) maximum volume: 15 Liters   maximum flow rate: 0.1 L/min (short term) current analytical method: Gas Chromatography; GC/FID method reference: OSHA Analytical Method (OSHA 79) method classification: Fully Validated note: Use these larger maximum volumes to monitor sub-ppm levels. Samples for 2-methoxyethyl acetate and/or for 2-ethoxyethyl acetate should be refrigerated upon receipt at the analytical laboratory. Wipe Sampling Method: sampling media: charcoal pad note: Seal in glass vial for shipment. All Trademarks are the property of their respective owners. Accessibility Assistance: Contact the OSHA Directorate of Science, Technology and Medicine at 202-693-2300 for assistance accessing PDF materials.