Department of Labor Seal photos representing the workforce - digital imageryŠ copyright 2001 photodisc, inc.
Department of Labor Seal www.osha.gov  [skip navigational links] Search    Advanced Search | A-Z Index
<< Chemical Sampling Information (CSI) Link to Printing InstructionsPrinting Instructions
Chemical Sampling Information (CSI) Chemical Sampling Information
2-Methoxyethyl acetate

Quick Links
Search
  
[use word(s)/phrase]
Table of Contents
By Name
A B C D E F G H I J K L M N
O P Q R S T U V W X Y Z


By CAS Number
General Description
    Synonyms: EGMEA; Ethylene glycol monomethyl ether acetate; Glycol monomethyl ether acetate; 2-Methoxyethanol acetate; Methyl Cellosolve® acetate

    OSHA IMIS Code Number: 1170
    IMIS Name History: Methyl Cellosolve® acetate prior to 7/26/2005

    Chemical Abstracts Service (CAS) Registry Number: 110-49-6

    NIOSH, Registry of Toxic Effects (RTECS) Identification Number: KL5950000

    Department of Transportation Regulation Number (49 CFR 172.101) and Guide: 1189 129

    NIOSH Pocket Guide to Chemical Hazards, Methyl Cellosolve® acetate: chemical description, physical properties, potentially hazardous incompatibilities, and more
Exposure Limits
    OSHA Permissible Exposure Limit (PEL) for General Industry: 29 CFR 1910.1000 Z-1 Table -- 25 ppm, 120 mg/m3 TWA; Skin

    OSHA Permissible Exposure Limit (PEL) for Construction Industry: 29 CFR 1926.55 Appendix A -- 25 ppm, 120 mg/m3 TWA; Skin

    OSHA Permissible Exposure Limit (PEL) for Maritime: 29 CFR 1915.1000 Table Z-Shipyards -- 25 ppm, 120 mg/m3 TWA; Skin

    American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 0.1 ppm, 0.5 mg/m3 TWA; Skin

    National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 0.1 ppm, 0.5 mg/m3 TWA; Skin
Health Factors
    NIOSH Immediately Dangerous To Life or Health Concentration (IDLH): 200 ppm

    Potential symptoms: Eye, nose, and throat irritation; coughing, shortness of breath, pulmonary edema; kidney, brain damage; dizziness, drowsiness, headache; dry skin; in animals: narcosis; reproductive, teratogenic effects; SKIN ABS; INGES ACUTE: Abdominal pain, nausea, vomiting; weakness; unconsciousness.

    Health Effects: Irritiation-Eyes, Nose, Throat, Skin---Mild (HE16); Blood disorders (HE12); CNS effects (HE7); Kidney damage (HE3); Suspected reproductive effects (HE5).

    Affected organs: Eyes, respiratory system, kidneys, brain, CNS, PNS, reproductive system, hematopoietic system.

    Note: The acetate ester is rapidly converted in the body to methyl cellusolve (2-methoxyethanol), which is further metabolized to aldehyde and acid metabolites that are thought to be involved in reproductive and developmental toxicity, including teratogenicity (see file for Methyl Cellosolve).

    Date Last Revised: 12/14/2004

    Literature Basis:
    • NIOSH Pocket Guide to Chemical Hazards: Methyl Cellosolve® acetate.
    • International Chemical Safety Cards (WHO/IPCS/ILO): 2-Methoxyethyl Acetate.
    • Johanson, G.: Toxicity review of ethylene glycol monomethyl ether and its acetate ester. Crit. Rev. Toxicol. 30(3): 307-345, 2000.
    • Pohanish, R.P. (editor): Methoxyethyl Acetate. In, Sittig's Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 2. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 1507-1509.
Monitoring Methods used by OSHA
    Laboratory Sampling/Analytical Method:

    • sampling media: Charcoal Tube (100/50 mg sections, 20/40 mesh)
      analytical solvent: (95:5) Methylene Chloride:Methanol
      maximum volume: 10 Liters   maximum flow rate: 0.1 L/min
      current analytical method: Gas Chromatography; GC/FID
      method reference: OSHA Analytical Method (OSHA 53)
      method classification: Fully Validated
      note: Samples for 2-methoxyethyl acetate and/or for 2-ethoxyethyl acetate should be refrigerated upon receipt at the analytical laboratory.

    • sampling media: Charcoal Tube (100/50 mg sections, 20/40 mesh)
      analytical solvent: (95:5) Methylene Chloride:Methanol
      maximum volume: 48 Liters   maximum flow rate: 0.1 L/min (long term)
      maximum volume: 15 Liters   maximum flow rate: 0.1 L/min (short term)
      current analytical method: Gas Chromatography; GC/FID
      method reference: OSHA Analytical Method (OSHA 79)
      method classification: Fully Validated
      note: Use these larger maximum volumes to monitor sub-ppm levels. Samples for 2-methoxyethyl acetate and/or for 2-ethoxyethyl acetate should be refrigerated upon receipt at the analytical laboratory.

    Wipe Sampling Method:

    • sampling media: charcoal pad
      note: Seal in glass vial for shipment.

All Trademarks are the property of their respective owners.

Accessibility Assistance: Contact the OSHA Directorate of Science, Technology and Medicine at 202-693-2300 for assistance accessing PDF materials.

 
Back to TopBack to Top www.osha.gov www.dol.gov

Contact Us | Freedom of Information Act | Customer Survey
Privacy and Security Statement | Disclaimers
Occupational Safety & Health Administration
200 Constitution Avenue, NW
Washington, DC 20210
Page last updated: 10/24/2007