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Chemical Sampling Information |
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| Manganese Tetroxide (as Mn) |
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General Description
Synonyms: Manganese oxide; Manganomanganic oxide; Trimanganese tetraoxide; Trimanganese tetroxide
OSHA IMIS Code Number: M101
Chemical Abstracts Service (CAS) Registry Number: 1317-35-7
NIOSH, Registry of Toxic Effects (RTECS) Identification Number: OP0895000
NIOSH Pocket Guide to Chemical Hazards, Manganese Tetroxide (as Mn): chemical description, physical properties, potentially hazardous incompatibilities, and more
Exposure Limits
OSHA Permissible Exposure Limit (PEL) for General Industry: 29 CFR 1910.1000 Z-1 Table -- 5 mg/m3 Ceiling [PEL listed under Manganese Compounds (as Mn) and Manganese Fume (as Mn)]
OSHA Permissible Exposure Limit (PEL) for Construction Industry: 29 CFR 1926.55 Appendix A -- 5 mg/m3 Ceiling [PEL listed under Manganese Compounds (as Mn) and Manganese Fume (as Mn)]
OSHA Permissible Exposure Limit (PEL) for Maritime: 29 CFR 1915.1000 Table Z-Shipyards -- 5 mg/m3 Ceiling [PEL listed under Manganese Compounds (as Mn) and Manganese Fume (as Mn)]
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 0.2 mg/m3 (TLV listed under Manganese and Inorganic Compounds, as Mn)
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 1 mg/m3 TWA; Appendix D - Substances With No Established RELs
Health Factors
Potential symptoms: Asthenia, insomnia, mental confusion; low-back pain; vomiting; malaise, lassitude; kidney damage; cough, pneumonitis; eye, skin redness; neurological and mental disorders (manganism).
Health Effects: Irritation-Eyes, Nose, Throat, Skin---Moderate (HE15); Cumulative CNS damage (HE7); Lung damage---Acute (HE11) and Cumulative (HE10).
Affected organs: Respiratory system, CNS, blood, kidneys.
Note:
Inhalational toxicokinetic studies with rats indicate achievement of higher levels of manganese in the olfactory bulb and striatal brain areas with Mn sulfate (soluble) than with Mn tetroxide (relatively insoluble).
Date Last Revised: 06/28/2004
Literature Basis:
- NIOSH Pocket Guide to Chemical Hazards: Manganese Tetroxide (as Mn).
- International Chemical Safety Cards (WHO/IPCS/ILO): Manganese oxide.
- EPA Air Toxics Website: Manganese Compounds. U.S. Environmental Protection Agency Technology Transfer Network.
- Dorman, D.C., Struve, M.F., James, R.A., Marshall, M.W., Parkinson, C.U. and Wong, B.A.: Influence of particle solubility on the delivery of inhaled manganese to the rat brain: manganese sulfate and manganese tetroxide pharmacokinetics following repeated (14-day) exposure. Toxicol. Appl. Pharmacol. 170(2): 79-87, 2001.
Monitoring Methods used by OSHA
Laboratory Sampling/Analytical Method:
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sampling media: Mixed Cellulose Ester Filter (MCEF) 0.8 microns
maximum volume: 960 Liters minimum volume: 480 Liters maximum flow rate: 2.0 L/min
current analytical method: Atomic Absorption Spectroscopy; AAS
method reference: OSHA Analytical Method (OSHA ID-121)
method classification: Fully Validated
alternate analytical method: Inductively Coupled Argon Plasma; ICP/DCP-AES
method reference: OSHA Analytical Method (OSHA ID-125G)
method classification: Fully Validated
note: Analytical method does not distinguish between dust and fume. When an analysis of a compound is requested, an elemental analysis is performed and reported as Manganese.
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