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Chemical Sampling Information (CSI)
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General Description

Synonyms: 2-Aminopropane; IPAM; Monoisopropylamine; 2-Propanamine; sec-Propylamine

OSHA IMIS Code Number: 1562

Chemical Abstracts Service (CAS) Registry Number: 75-31-0

NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: NT8400000

Department of Transportation Regulation Number (49 CFR 172.101) and Guide: 1221 132

NIOSH Pocket Guide to Chemical Hazards, Isopropylamine: chemical description, physical properties, potentially hazardous incompatibilities, and more


Exposure Limits

OSHA Permissible Exposure Limit (PEL):
General Industry: 29 CFR 1910.1000 Z-1 Table -- 5 ppm, 12 mg/m3 (TWA)

Construction Industry: 29 CFR 1926.55 Appendix A -- 5 ppm, 12 mg/m3 (TWA)

Maritime: 29 CFR 1915.1000 Table Z-Shipyards -- 5 ppm, 12 mg/m3 (TWA)
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 5 ppm, 12 mg/m3 (TWA); 10 ppm, 24 mg/m3 (STEL)

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): Appendix D - Substances With No Established RELs


Health Factors

Potential Symptoms: Eye, nose, throat, skin irritation; pulmonary edema; visual disturbance; skin, eye burns; dermatitis

Health Effects: Irritation-Eye, Nose, Throat, Skin---Marked (HE14)

Affected Organs: Respiratory system, skin, eyes

NIOSH/OSHA/DOE Health Guideline: Isopropylamine


Monitoring Methods used by OSHA

Laboratory Sampling/Analytical Method:
  • sampling media: Coated XAD-2 Tube (80/40 sections, 20/60 mesh); coating is 10% (w/w) 1-Naphthylisothiocyanate (NITC)
    analytical solvent: Dimethylformamide
    maximum volume: 20 Liters
    maximum flow rate: 1.0 L/min (TWA)
    maximum volume: 1.5 Liters
    maximum flow rate: 1.0 L/min (STEL)
    current analytical method: High Performance Liquid Chromatography; HPLV/UV
    method reference: OSHA Analytical Method (OSHA PV2126)
    method classification: Partially Validated
    sampling media: Midget Fritted Glass Bubbler (MFGB) containing 10 mL of 0.05 M H2SO4.
    maximum volume: 100 Liters
    maximum flow rate:
    1.0 L/min (TWA)
    maximum volume: 15 Liters
    maximum flow rate: 1.0 L/min (STEL)
    current analytical method: Gas Chromatography; GC/FID
    method reference: NIOSH Analytical Method NIOSH S-147
    method classification: Fully Validated
On-Site Sampling Techniques/Methods:
    device: Detector Tube
    manufacturer: AUER/MSA
    model/type: Triethylamine-5, MSA P/N 804134, AUER P/N 5086-816
    sampling information: follow manufacturer's instructions
    upper measurement limit: 30 ppm
    detection limit: approximately 1 ppm
    overall uncertainty: unknown
    method reference: on-site air secondary (manufacturer)
    device: Detector Tube
    manufacturer: Gastec
    model/type: 180
    sampling information: 1 stroke
    upper measurement limit: 110 ppm
    detection limit: 1 ppm
    overall uncertainty: 16.4% for 6 to 22 ppm, 8.2% for 22 to 110 ppm
    method reference: on-site air secondary (manufacturer)
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