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Isobutyl Alcohol Chemical Sampling Information:
Isobutyl Alcohol

General Description
    Synonyms: Isobutanol; IBA; 2-Methyl-1-propanol; Isopropylcarbinol

    OSHA IMIS Code Number: 1536

    Chemical Abstracts Service (CAS) Registry Number: 78-83-1

    NIOSH, Registry of Toxic Effects (RTECS) Identification Number: NP9625000

    Department of Transportation Regulation Number (49 CFR 172.101) and Guide: 1212 129

    NIOSH Pocket Guide to Chemical Hazards, Isobutyl Alcohol: chemical description, physical properties, potentially hazardous incompatibilities, and more
Exposure Limits
    OSHA Permissible Exposure Limit (PEL) for General Industry: 29 CFR 1910.1000 Z-1 Table -- 100 ppm, 300 mg/m3 TWA

    OSHA Permissible Exposure Limit (PEL) for Construction Industry: 29 CFR 1926.55 Appendix A -- 100 ppm, 300 mg/m3 TWA

    OSHA Permissible Exposure Limit (PEL) for Maritime: 29 CFR 1915.1000 Table Z-Shipyards -- 100 ppm, 300 mg/m3 TWA

    American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 50 ppm, 152 mg/m3 TWA (Listed under Isobutanol)

    National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 50 ppm, 150 mg/m3 TWA
Health Factors
    NIOSH Immediately Dangerous To Life or Health Concentration (IDLH): 1,600 ppm

    Potential symptoms: Eye, throat irritation; headaches; dizziness; drowsiness; eye redness, pain, blurred vision; skin irritation, cracking, dermatitis; in animals: narcosis; INGES ACUTE: nausea, vomiting, diarrhea.

    Health Effects: Irritation-Eye, Nose, Throat, Skin---Moderate (HE15).

    Affected organs: Eyes, skin, respiratory system, CNS

    Notes: 1) Above 28°C, explosive vapor/air mixtures may be formed. 2) Listed among FDA's "food additives permitted for direct addition to food for human consumption" (21CFR 172.515)

    Date Last Revised: 02/04/2004

    Literature Basis:
Monitoring Methods used by OSHA
    Laboratory Sampling/Analytical Method:

    • sampling media: Charcoal Tube (100/50 mg sections, 20/40 mesh)
      analytical solvent: (99:1) Carbon Disulfide:Isopropanol
      alternative solvent: (99:1) Carbon Disulfide:Dimethylformamide
      alternative solvent: (95:5) Methylene Chloride:Methanol
      maximum volume: 10 Liters   maximum flow rate: 0.2 L/min
      current analytical method: Gas Chromatography; GC/FID
      method reference: NIOSH Analytical Method (NIOSH 1401)
      method classification: Fully Validated

    On-Site Sampling Techniques/Methods:

    • device: Detector Tube
      manufacturer: Gastec
      model/type: 116
      sampling information: 2 strokes
      upper measurement limit: 150 ppm
      detection limit: 1 ppm
      overall uncertainty: 25% for 5 to 50 ppm, 16% for 50 to 150 ppm
      method reference: on-site air secondary (manufacturer)


    • device: Detector Tube
      manufacturer: Matheson-Kitagawa
      model/type: 8014-208U
      sampling information: 3 strokes
      upper measurement limit: 100 ppm
      detection limit: approximately 2 ppm
      overall uncertainty: unknown
      method reference: on-site air secondary (manufacturer)
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Page last updated: 03/16/2005