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Chemical Sampling Information |
| Isoamyl acetate |
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General Description
Synonyms: Banana oil; Isopentyl alcohol, acetate; 3-Methyl-1-butanol acetate, 3-Methylbutyl ester of acetic acid, 3-Methylbutyl ethanoate
OSHA IMIS Code Number: 1530
Chemical Abstracts Service (CAS) Registry Number: 123-92-2
NIOSH, Registry of Toxic Effects (RTECS) Identification Number: NS9800000
Department of Transportation Regulation Number (49 CFR 172.101) and Guide: 1104 129 [27 KB, PDF]
NIOSH Pocket Guide to Chemical Hazards, Isoamyl Acetate: chemical description, physical properties, potentially hazardous incompatibilities, and more
Exposure Limits
OSHA Permissible Exposure Limit (PEL) for General Industry: 29 CFR 1910.1000 Z-1 Table -- 100 ppm, 525 mg/m3 TWA
OSHA Permissible Exposure Limit (PEL) for Construction Industry: 29 CFR 1926.55 Appendix A -- 100 ppm, 525 mg/m3 TWA
OSHA Permissible Exposure Limit (PEL) for Maritime: 29 CFR 1915.1000 Table Z-Shipyards -- 100 ppm, 525 mg/m3 TWA
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 50 ppm, 266 mg/m3 TWA; 100 ppm, 532 mg/m3 STEL (Listed under Pentyl acetate, All isomers)
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 100 ppm, 525 mg/m3 TWA
Health Factors
NIOSH Immediately Dangerous To Life or Health Concentration (IDLH): 1000 ppm
Potential symptoms: Irritation of eyes, skin, nose, throat; dermatitis; cough, sore throat; headache, drowsiness, weakness; eye redness, pain; dry skin; in animals: narcosis
Health Effects: Irritation-Eye, Nose, Throat, Skin---Moderate (HE15); CNS effects (HE7)
Affected organs: Eyes, skin, respiratory system, CNS
Notes:
- Listed among FDA’s “food additives permitted for direct addition to food for human consumption” (21 CFR 172.515).
- Isoamyl acetate is used as a standard odorant in olfactory research and function testing, as well as in respirator fit testing (29 CFR 1910.134 Appendix A).
Date Last Revised: 11/06/2006
Literature Basis:
- NIOSH Pocket Guide to Chemical Hazards: Isoamyl Acetate.
- International Chemical Safety Cards (WHO/IPCS/ILO): Isoamyl acetate.
- Bensafi, M., Rouby, C., Farget, V., Bertrand, B., Vigouroux, M. and Holley, A.: Autonomic nervous system responses to odours: the role of pleasantness and arousal. Chem. Senses 27(8): 703-709, 2002.
- Grossmann, N., Brin, I., Aizenbud, D., Sichel, J.Y., Gross-Isseroff, R. and Steiner, J.: Nasal aikrflow and olfactory function after the repair of cleft palate (with and without cleft lip). Oral. Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 100(5): 539-544, 2005.
- Pohanish, R.P. (editor): Isoamyl Acetate. In, Sittig’s Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 2. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 1319-1320.
Monitoring Methods used by OSHA
Laboratory Sampling/Analytical Method:
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sampling media: Charcoal Tube (100/50 mg sections, 20/40 mesh)
analytical solvent: (99:1) Carbon disulfide:dimethyl formamide
maximum volume: 24 Liters maximum flow rate: 0.1 L/min
minimum time: 15 Minutes maximum flow rate: 0.1 L/min
current analytical method: Gas Chromatography; GC/FID
method reference: OSHA Analytical Method (OSHA PV2142)
method classification: Partially Validated
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sampling media: Charcoal Tube (100/50 mg sections, 20/40 mesh)
analytical solvent: Carbon disulfide
maximum volume: 10 Liters maximum flow rate: 0.2 L/min
current analytical method: Gas Chromatography; GC/FID
method reference: NIOSH Analytical Method (NIOSH 1450) [107 KB, PDF]
method classification: Fully Validated
note: Samples must be refrigerated for shipment to laboratory.
On-Site Sampling Techniques/Methods:
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device: Detector Tube
manufacturer: Gastec
model/type: 147
sampling information: 4 minutes per pump stroke
upper measurement limit: 200 ppm
detection limit: 2 ppm
overall uncertainty: 15% (10-50 ppm) 10% (50-200 ppm)
method reference: # on-site air secondary (manufacturer)
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