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Chemical Sampling Information (CSI)
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General Description

OSHA IMIS Code Number: 0861

Chemical Abstracts Service (CAS) Registry Number: 334-88-3

NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: PA7000000; 47875

Chemical Description and Physical Properties:
    Yellow gas, or liquid under pressure.
    molecular weight: 42
    boiling point: -9°F
    melting point: -229°F
Incompatibilities: Alkali metals, drying agents such as calcium sulfate

Exposure Limits

OSHA Permissible Exposure Limit (PEL):
General Industry: 0.2 ppm, 0.4 mg/m3

Construction Industry: 0.2 ppm, 0.4 mg/m3 TWA
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 0.2 ppm, 0.34 mg/m3 TWA; Appendix A2 (Suspected Human Carcinogen)

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 0.2 ppm TWA

Health Factors

Carcinogenic Classification:
International Agency for Research on Cancer (IARC): Group 3, not classifiable as to its carcinogenicity to humans [75 KB PDF, 24 pages]
Potential Symptoms: Coughing, shortness of breath; headaches; flushed skin, fever; chest pain, pulmonary edema, pneumonitis; irritated eyes; asthma; fatigue

Health Effects: Acute lung damage (HE11) Irritation-Eyes, Nose, Throat, Skin---Marked (HE14)

Affected Organs: Respiratory system, eyes, skin

Date Last Revised: 12/01/1998

NIOSH/OSHA/DOE Health Guideline: Diazomethane

Monitoring Methods used by OSHA

Laboratory Sampling/Analytical Method:
  • sampling media: Coated XAD-2 Tube (100/50 mg sections, 20/50 mesh); Coating is 1% (w/w) Octanoic Acid.
    analytical solvent: Carbon Disulfide
    maximum volume: 30 Liters
    maximum flow rate: 0.2 L/min
    current analytical method: Gas Chromatography; GC/FID
    method reference: 1 NIOSH 2515 [29 KB PDF, 4 pages]
    sampling and analytical error: 0.14
    method classification: Fully Validated

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Page last updated: 06/01/2006

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