Synonyms: alpha-Naphthyl thiourea; alpha-Naphthyl thiocarbamide; 1-Naphthyl-thiourea; N(1-Naphthyl)-2-thiourea; Alphanaphthyl Thiourea
OSHA IMIS Code Number: 0235
Chemical Abstracts Service (CAS) Registry Number: 86-88-4
NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: YT9275000; 86993
Department of Transportation Regulation Number (49 CFR 172.101) and Guide: UN1651 153 Poison
Chemical Description and Physical Properties:
colorless, odorless solid
molecular weight: 202
vapor pressure: approx. 0 mm
boiling point: Decomposes
melting point: 388°F
Incompatibilities: Strong oxidizers
OSHA Permissable Exposure Limit (PEL):
General Industry: 0.3 mg/m3
Construction Industry: 0.3 mg/m3 TWA
American Conference of Governmental Industrial Hygenists (ACGIH) Threshold Limit Value (TLV): 0.3 mg/m3 TWA; Appendix A4 (Not Classifiable as a Human Carcinogen)
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 0.3 mg/m3 TWA
Carcinogenic Classification:
International Agency for Research on Cancer (IARC): Group 3, not classifiable as to its carcinogenicity to humans (alpha-Naphthylthiourea)
Potential Symptoms: Vomiting; dyspnea; cyanosis; coarse pulmonary rales; mild liver damage
Health Effects: Cumulative Endocrine (thyroid and adrenal) damage (HE3) LD50 (oral, rat) 6 mg/kg
Skin Irritation: Eczema
Affected Organs: Respiratory system
Primary Laboratory Sampling/Analytical Method (SLC1):
-
sampling media: Polytetrafluoroethylene (FA) Filter, 1.0 micron
analytical solvent: Methanol
maximum volume: 480 Liters
maximum flow rate: 2.0 L/min
current analytical method: High Performance Liquid Chromatography; HPLC/UL58.
method reference: 1 (NIOSH S-276)
sampling and analytical error: 0.09
method classification: Fully Validated
Conditions: column: C18 mobile phase: 50:50 Methanol: Water detector wavelength: 254nm detection limit: 0.13 mg/m3
Wipe Sampling Method:
-
sampling media: Glass Fiber Filter
analytical solvent: Dry
Bulk Method:
- Limit the amount of bulk submitted to one gram or one mL.
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