Chemical Sampling Information
	n-Amyl acetate
Quick Links General Description Exposure Limits Health Factors Monitoring Search    [use word(s)/phrase ] Table of Contents By Name A B C D E F G H I J K L M N O P Q R S T U V W X Y Z By CAS Number General Description Synonyms: Acetic acid, pentyl ester; Amyl acetic ester; Amyl acetic ether; 1-Pentanol acetate; 1-Pentyl acetate; Pentyl ester of acetic acid; Primary amyl acetate OSHA IMIS Code Number: 0190 Chemical Abstracts Service (CAS) Registry Number: 628-63-7 NIOSH, Registry of Toxic Effects (RTECS) Identification Number: AJ1925000 Department of Transportation Regulation Number (49 CFR 172.101) and Guide: 1104 129 [27 KB, PDF] NIOSH Pocket Guide to Chemical Hazards, n-Amyl Acetate: chemical description, physical properties, potentially hazardous incompatibilities, and more Exposure Limits OSHA Permissible Exposure Limit (PEL) for General Industry: 29 CFR 1910.1000 Z-1 Table -- 100 ppm, 525 mg/m3 TWA OSHA Permissible Exposure Limit (PEL) for Construction Industry: 29 CFR 1926.55 Appendix A -- 100 ppm, 525 mg/m3 TWA OSHA Permissible Exposure Limit (PEL) for Maritime: 29 CFR 1915.1000 Table Z-Shipyards -- 100 ppm, 525 mg/m3 TWA American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 50 ppm, 266 mg/m3 TWA; 100 ppm, 532 mg/m3 STEL (Listed under Pentyl acetate, All Isomers) National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 100 ppm, 525 mg/m3 TWA Health Factors NIOSH Immediately Dangerous To Life or Health Concentration (IDLH): 1,000 ppm Potential symptoms: Irritation of eyes, nose; cough, sore throat; dry skin, dermatitis; headache; possible CNS depression, dizziness, drowsiness, narcosis Health Effects: Irritation-Eye, Nose, Throat---Moderate (HE15); Narcosis (HE8); Explosive, Flammable (HE18) Affected organs: Eyes, skin, respiratory system, CNS Notes: Above 25ºC, explosive vapor/air mixtures may be formed. The concentration of amyl acetate causing a 50% decrease in the respiratory rate of mice (a measure of sensory irritation) was reported to be 1531 ppm. Neurotoxicity studies in rats exposed to amyl acetate by inhalation 6 hours/day for at least 65 days reported a NOAEL of at least 1200 ppm (the highest concentration tested). Date Last Revised: 06/30/2006 Literature Basis: NIOSH Pocket Guide to Chemical Hazards: n-Amyl Acetate. International Chemical Safety Cards (WHO/IPCS/ILO): n-Amyl acetate. Alarie, Y.: Dose-response analysis in animal studies: prediction of human responses. Environ. Health Perspect. 42: 9-13, 1981. Gill, M.W., Tyler, T.R. and Beyrouty, P.C.: Subchronic inhalation neurotoxicity study of amyl acetate in rats. J. Appl. Toxicol. 20(6): 463-469, 2000. Pohanish, R.P. (editor): Amyl Acetates. In, Sittig’s Handbook of Toxic and Hazardous Chemicals and Carcinogens, Fourth Ed., Vol. 1. Norwich, NY: Noyes Publications, William Andrew Publishing, 2002, pp. 199-201. Monitoring Methods used by OSHA Laboratory Sampling/Analytical Method: sampling media: Charcoal Tube (100/50 mg sections, 20/40 mesh) analytical solvent: (99:1) Carbon disulfide:dimethyl formamide maximum volume: 24 Liters   maximum flow rate: 0.1 L/min minimum time: 15 Minutes   maximum flow rate: 0.1 L/min current analytical method: Gas Chromatography; GC/FID method reference: OSHA Analytical Method (OSHA PV2142) method classification: Partially Validated sampling media: Charcoal Tube (100/50 mg sections, 20/40 mesh) analytical solvent: Carbon disulfide maximum volume: 10 Liters   maximum flow rate: 0.2 L/min current analytical method: Gas Chromatography; GC/FID method reference: NIOSH Analytical Method (NIOSH 1450) [107 KB, PDF] method classification: Fully Validated note: Samples must be refrigerated for shipment to laboratory. On-Site Sampling Techniques/Methods: device: Detector Tube manufacturer: Gastec model/type: 147 sampling information: 4 minutes per pump stroke upper measurement limit: 200 ppm detection limit: 2 ppm overall uncertainty: 15% (10-50 ppm) 10% (50-200 ppm) method reference: # on-site air secondary (manufacturer) All Trademarks are the property of their respective owners. Accessibility Assistance: Contact the OSHA Directorate of Science, Technology and Medicine at 202-693-2300 for assistance accessing PDF materials.