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Safety and Health Topics: |
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| Aldrin |
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General Description
Synonyms: 1,2,3,4,10,10-Hexachloro-1,4,4a,5,8,8a-hexahydro-exo-1,4-endo-5,8-dimethanonaphthalene; Octalene; Aldrite; Aldrosol; HHDN; Seedrin; NCI-C00044
OSHA IMIS Code Number: 0125
Chemical Abstracts Service (CAS) Registry Number: 309-00-2
NIOSH, Registry of Toxic Effects (RTECS) Identification Number: IO2100000
Department of Transportation Regulation Number (49 CFR 172.101): 2761 151
NIOSH Pocket Guide to Chemical Hazards, Aldrin: chemical description, physical properties, potentially hazardous incompatibilities, and more
Exposure Limits
OSHA Permissible Exposure Limit (PEL) for General Industry: 29 CFR 1910.1000 Z-1 Table -- 0.25 mg/m3 TWA; Skin
OSHA Permissible Exposure Limit (PEL) for Maritime: 29 CFR 1915.1000 Table Z-Shipyards -- 0.25 mg/m3 TWA; Skin
American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV): 0.25 mg/m3 TWA; Skin; Appendix A3 (Confirmed Animal Carcinogen with Unknown Relevance to Humans)
National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL): 0.25 mg/m3 TWA; Skin; Appendix A - Potential Occupational Carcinogen
Health Factors
International Agency for Research on Cancer (IARC) carcinogenic classification: Group 3, not classifiable as to its carcinogenicity to humans.
NIOSH Immediately Dangerous To Life or Health Concentration (IDLH): 25 mg/m3
Potential symptoms: Headache, dizziness; nausea, vomiting, malaise; mild erythema of skin; impairment of memory, emotional disturbances; tremors, hyperexcitability, myoclonic jerks of limbs; clonic-tonic convulsions, coma, respiratory failure.(carcinogenic)
Health Effects: CNS Disturbances (HE7); LD50 (oral, rat) 39-45 mg/kg; (dermal, rat) 98 mg/kg.
Affected organs: CNS, liver, kidneys.
Note: Metabolized in the body to dieldrin, also a previously used insecticide. Neither has been produced or used since 1989, but may remain in buildings treated for termites or in chemical dumping sites.
Date Last Revised: 01/08/2002
Literature Basis:
- (impairment of memory, emotional disturbances, tremors, hyperexcitability, and seizures)
Sullivan, J.B., Jr., and Van Ert, M.: Organochlorine pesticides (Chapter 102). Materials Toxicology, Clinical Principles of Environmental Health, Sullivan, J.B. Jr., and Krieger, G.R. eds. Baltimore: Williams & Wilkins, pp. 1042-1047, 1992.
- (headache, dizziness, nausea, vomiting; skin erythema)
Bus, J.S. and Leber, A.P.: Miscellaneous chlorinated hydrocarbon pesticides (Chapter 69), in Patty's Toxicology, 5th Ed., Vol. 5, E. Bingham, B. Cohrssen and C.H. Powell, eds. New York: John Wiley & Sons, Inc., pp. 635-640, 2001.
- (acute toxicity data - LD50s)
Monitoring Methods used by OSHA
Laboratory Sampling/Analytical Method:
sampling media: Glass Fiber Filter (37 mm) in series with Midget Fritted Glass Bubbler (MFGB) containing 15mL Ethylene Glycol
maximum volume: 240 Liters maximum flow rate: 1.0 L/min
current analytical method: Gas Chromatography; GC/ECD
method reference: OSHA modified NIOSH Manual of Analytical Methods (OSHA modified NIOSH 5502)
method classification: Partially Validated
Wipe sampling: Yes, with Glass Fiber Filter. Solvent: Dry
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| Revised: 07 August 2003 |
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