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Chemical Sampling Information (CSI)
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General Description

Synonyms: Acetyl methyl carbinol; 1-Hydroxyethyl methyl ketone; gamma-Hydroxy-beta-oxobutane; 3-hydroxy-2-butanone; 2,3-butanolone; Dimethylketol

OSHA IMIS Code Number: A624
(IMIS Name History: Acetylmethycarbinol prior to 1/28/09)

Chemical Abstracts Service (CAS) Registry Number: 513-86-0

NIOSH Registry of Toxic Effects of Chemical Substances (RTECS) Identification Number: EL8790000

Department of Transportation Regulation Number (49 CFR 172.101) and 2012 Emergency Response Guidebook [4 MB PDF, 392 pages]: 2621 127

Physical and Chemical Properties

physical description: light yellow liquid
molecular formula: C4H8O2
molecular weight: 88.10
boiling point: 148°C
melting point: 15°C
flash point: 50°C

Exposure Limits and Health Effects

Exposure Limit

Limit Values

HE Codes

Health Factors and Target Organs

OSHA Permissible Exposure Limit (PEL)

Not established

 

 

National Institute for Occupational Safety and Health (NIOSH) Recommended Exposure Limit (REL)

Not established

 

 

American Conference of Governmental Industrial Hygienists (ACGIH) Threshold Limit Value (TLV)

Not established

 

 

CAL/OSHA PELs

Not established

 

 

National Toxicology Program (NTP) carcinogenic classification: Not listed

International Agency for Research on Cancer (IARC) carcinogenic classification: Not listed

U.S. Environmental Protection Agency (EPA) carcinogenic classification: Not listed

EPA Inhalation Reference Concentration (RfC): Not listed

Agency for Toxic Substances and Disease Registry (ATSDR) Inhalation Minimal Risk Level (MRL): Not established

NIOSH Immediately Dangerous to Life or Health (IDLH) concentration: Not established

Notes on Other Potential Health Effects and Hazards

    1. Occupational lung diseases have been reported in workers in the microwave popcorn production industry. Several volatile organic compounds, including acetoin, are released from the butter flavoring (NTP 2007).

Date Last Revised: 9/6/2012

Literature Basis


Monitoring Methods used by OSHA

Primary Laboratory Sampling/Analytical Method (SLC1):

  • sampling media: Two specially dried Silica Gel Tubes in series. Each tube has a single 600-mg 20/40 mesh section and a glass-fiber filter, the filter faces forward when sampling. SKC 226-183, or equivalent. Use an opaque tube holder or wrap tubes with aluminum foil or other opaque material while sampling.
    maximum volume: 9 liters
    minimum flow rate: 0.05 L/min for long-term sampling; 3 liters at 0.2 L/min for short-term sampling.
    note: Separate the two tubes and cap both ends of each tube as soon as possible after sampling. Individually seal the two tubes. Protect tubes from light after sampling.

    • analytical method 1: Gas Chromatography; GC/ECD
      analytical solvent: (95:5) ethanol:water with 2 mg/mL PFBHA reagent
      method reference: OSHA Analytical Method (OSHA 1012)
      method classification: Fully Validated

    • analytical method 2: Gas Chromatography; GC/FID
      analytical solvent: (95:5) ethanol:water
      method reference: OSHA Analytical Method (OSHA 1013)
      method classification: Fully Validated

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